Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 2/20 | 0.39 |
| ▸ | PLK4 | O00444 | 4/20 | 0.38 |
| ▸ | PAK4 | O96013 | 4/20 | 0.38 |
| ▸ | NOS1 | P29475 | 4/20 | 0.36 |
| ▸ | METAP2 | P50579 | 2/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25322760 | 1.00 | ALDH1A1 (0.40) | ALDH1A1KDM4EMEN1KMT2AAXL | |
| SCHEMBL13153124 | 0.80 | KMT2A (0.46) | ALDH1A1KDM4EMEN1KMT2APLK4 | |
| SCHEMBL24348557 | 0.77 | PLK4 (0.38) | ALDH1A1KDM4EPLK4PAK4NOS1 | |
| SCHEMBL23841035 | 0.77 | NCF1 (0.43) | ALDH1A1KDM4EMEN1KMT2APLK4 | |
| SCHEMBL31555833 | 0.77 | PLK4 (0.41) | AXLPLK4PAK4NOS1METAP2 | |
| SCHEMBL19966396 | 0.77 | FGFR1 (0.39) | ALDH1A1PLK4PAK4SMN1; SMN2L3MBTL1 | |
| SCHEMBL26661515 | 0.76 | TRPA1 (0.39) | ALDH1A1PLK4PAK4SMN1; SMN2IDO1 | |
| SCHEMBL20656567 | 0.73 | ALDH1A1 (0.39) | ALDH1A1KDM4EPLK4PAK4SMN1; SMN2 | |
| SCHEMBL29514216 | 0.73 | NOS1 (0.37) | ALDH1A1AXLNOS1METAP2CSNK2A1 | |
| SCHEMBL26603095 | 0.73 | NOS1 (0.37) | ALDH1A1AXLNOS1METAP2CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119137118-A | Antagonists of adenosine receptors | 阿道尔克斯治疗有限公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-116635380-A | PPARgamma modulators and methods of use | 卫材R&D管理有限公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-116490503-A | Casein kinase 1 delta modulators | 詹森药业有限公司 | 2023-07-25 | — | — | CN | disclosed |