Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK4 | O00444 | 2/20 | 0.38 |
| ▸ | PAK4 | O96013 | 2/20 | 0.38 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.33 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13153124 | 0.80 | KMT2A (0.46) | PLK4PAK4ALDH1A1SMN1; SMN2PDPK1 | |
| SCHEMBL30509508 | 0.77 | ALDH1A1 (0.40) | PLK4PAK4NOS1ALDH1A1SMN1; SMN2 | |
| SCHEMBL29442177 | 0.77 | NOS1 (0.36) | PLK4PAK4NOS1ALDH1A1SMN1; SMN2 | |
| SCHEMBL19966396 | 0.77 | FGFR1 (0.39) | PLK4PAK4ALDH1A1SMN1; SMN2PDPK1 | |
| SCHEMBL25322760 | 0.77 | ALDH1A1 (0.40) | PLK4PAK4NOS1ALDH1A1SMN1; SMN2 | |
| SCHEMBL22554143 | 0.77 | PLK4 (0.41) | PLK4PAK4NOS1SMN1; SMN2CHEK1 | |
| SCHEMBL23841035 | 0.77 | NCF1 (0.43) | PLK4PAK4ALDH1A1PDPK1CHEK1 | |
| SCHEMBL23780741 | 0.77 | NOS1 (0.36) | PLK4PAK4NOS1ALDH1A1SMN1; SMN2 | |
| SCHEMBL26661515 | 0.76 | TRPA1 (0.39) | PLK4PAK4ALDH1A1SMN1; SMN2PDPK1 | |
| SCHEMBL20656567 | 0.73 | ALDH1A1 (0.39) | PLK4PAK4ALDH1A1SMN1; SMN2PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022058920-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2022-03-24 | — | — | WO | disclosed |