Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PI4KA | P42356 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | BCR | P11274 | 1/20 | 0.33 |
| ▸ | XPO1 | O14980 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 7/20 | 0.33 |
| ▸ | ATF1 | P18846 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20660682 | 0.76 | NT5E (0.44) | NT5ETRPV4PIK3CDPIK3CAPIK3CB | |
| SCHEMBL31405448 | 0.74 | ALDH1A1 (0.37) | PIK3CDKDM4EALDH1A1SMN1; SMN2EGFR | |
| SCHEMBL1320635 | 0.74 | ALDH1A1 (0.37) | PIK3CDKDM4EALDH1A1SMN1; SMN2EGFR | |
| SCHEMBL22057382 | 0.71 | CYP1A2 (0.41) | KDM4EALDH1A1SMN1; SMN2EGFR | |
| SCHEMBL20660629 | 0.70 | NT5E (0.37) | NT5EGABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL17959 | 0.70 | GABRA1 (0.50) | GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL31038939 | 0.70 | GABRA1 (0.50) | GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL30876122 | 0.69 | TGFBR1 (0.48) | GABRA1GABRG2GABRB3GABRA3TRPV4 | |
| SCHEMBL20660771 | 0.69 | NT5E (0.36) | NT5EXPO1NFKB1ATF1KDM4E | |
| SCHEMBL20660632 | 0.69 | BACE1 (0.50) | XPO1NFKB1ATF1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12258354-B2 | AhR modulators | IDEAYA BIOSCIENCES, INC. (US) | 2025-03-25 | — | — | US | disclosed |
| EP-3749669-B3 | AHR MODULATORS | IDEAYA BIOSCIENCES INC (US) | 2024-09-04 | — | — | EP | disclosed |
| CN-111683950-B | AhR modulators | 伊迪亚生物科学有限公司 | 2024-04-16 | — | — | CN | disclosed |
| EP-4219495-A1 | AHR MODULATORS | Ideaya Biosciences, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| EP-4219495-A1 | AHR MODULATORS | Ideaya Biosciences, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| EP-3749669-B1 | AHR MODULATORS | IDEAYA BIOSCIENCES INC (US) | 2023-03-08 | — | — | EP | disclosed |
| US-20230039955-A1 | AhR MODULATORS | IDEAYA BIOSCIENCES, INC. | 2023-02-09 | — | — | US | disclosed |
| US-20230039955-A1 | AhR MODULATORS | IDEAYA BIOSCIENCES, INC. | 2023-02-09 | — | — | US | disclosed |
| US-11548867-B2 | Amido compounds as AhR modulators | IDEA YA BIOSCIENCES, INC. (US) | 2023-01-10 | — | — | US | disclosed |
| US-11548867-B2 | Amido compounds as AhR modulators | IDEA YA BIOSCIENCES, INC. (US) | 2023-01-10 | — | — | US | disclosed |
| US-10815250-B2 | AhR modulators | IDEAYA BIOSCIENCES, INC. (US) | 2020-10-27 | — | — | US | disclosed |
| US-10815250-B2 | AhR modulators | IDEAYA BIOSCIENCES, INC. (US) | 2020-10-27 | — | — | US | disclosed |
| WO-2020018848-A1 | METHODS OF CULTURING AND/OR EXPANDING STEM CELLS AND/OR LINEAGE COMMITTED PROGENITOR CELLS USING AMIDO COMPOUNDS | IDEAYA BIOSCIENCES, INC. (US) | 2020-01-23 | — | — | WO | disclosed |
| WO-2020018848-A1 | METHODS OF CULTURING AND/OR EXPANDING STEM CELLS AND/OR LINEAGE COMMITTED PROGENITOR CELLS USING AMIDO COMPOUNDS | IDEAYA BIOSCIENCES, INC. (US) | 2020-01-23 | — | — | WO | disclosed |
| US-20190270754-A1 | AhR MODULATORS | IDEAYA BIOSCIENCES, INC. | 2019-09-05 | — | — | US | disclosed |
| US-20190270754-A1 | AhR MODULATORS | IDEAYA BIOSCIENCES, INC. | 2019-09-05 | — | — | US | disclosed |
| WO-2019156987-A1 | AhR MODULATORS | IDEAYA BIOSCIENCES, INC. (US) | 2019-08-15 | — | — | WO | disclosed |
| WO-2019156987-A1 | AhR MODULATORS | IDEAYA BIOSCIENCES, INC. (US) | 2019-08-15 | — | — | WO | disclosed |
| WO-2019018562-A1 | AMIDO COMPOUNDS AS AhR MODULATORS | IDEAYA BIOSCIENCES, INC. (US) | 2019-01-24 | — | — | WO | disclosed |
| WO-2019018562-A1 | AMIDO COMPOUNDS AS AhR MODULATORS | IDEAYA BIOSCIENCES, INC. (US) | 2019-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230039955-A1 | AhR MODULATORS | AHR, ARNT, RORB | NT5E 2896/4885GABRA1 1252/4885GABRG2 1539/4885 |
| US-12258354-B2 | AhR modulators | AHR, ARNT, RORB | NT5E 2923/4885GABRA1 1260/4885GABRG2 1543/4885 |
| US-10815250-B2 | AhR modulators | AHR, ARNT, RORB | NT5E 2923/4885GABRA1 1260/4885GABRG2 1543/4885 |
| US-11548867-B2 | Amido compounds as AhR modulators | AHR, ARNT, RXRB | NT5E 2796/4885GABRA1 1561/4885GABRG2 1084/4885 |
| US-20190270754-A1 | AhR MODULATORS | AHR, ARNT, RORB | NT5E 2923/4885GABRA1 1260/4885GABRG2 1543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.