Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 2/20 | 0.34 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12315918 | 0.76 | TRPM8 (0.41) | CYP2C19LMNAALDH1A1 | |
| SCHEMBL28876472 | 0.75 | TSHR (0.42) | GABBR2GABBR1CYP2C19LMNAALDH1A1 | |
| SCHEMBL1053552 | 0.72 | LMNA (0.43) | GABBR2GABBR1CYP2C19LMNAGABRR1 | |
| SCHEMBL2772463 | 0.72 | LMNA (0.34) | GABBR2GABBR1CYP2C19LMNA | |
| SCHEMBL11348244 | 0.70 | GABBR2 (0.37) | GABBR2GABBR1CYP2C19LMNAALDH1A1 | |
| SCHEMBL5974203 | 0.69 | — | — | |
| SCHEMBL9713369 | 0.69 | FDPS (0.41) | — | |
| SCHEMBL8353170 | 0.69 | ALDH1A1 (0.44) | CYP2C19LMNAALDH1A1 | |
| SCHEMBL11343996 | 0.67 | LMNA (0.42) | CYP2C19LMNAALDH1A1 | |
| SCHEMBL7871737 | 0.67 | LMNA (0.42) | CYP2C19LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3431094-A1 | CROSSLINKED CATION EXCHANGE POLYMERS, COMPOSITIONS AND USE IN TREATING HYPERKALEMIA | Vifor Pharma Innovation Ltd. (CH) | 2019-01-23 | — | — | EP | disclosed |