Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | METAP2 | P50579 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HTR1E | P28566 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | PLAU | P00749 | 3/20 | 0.41 |
| ▸ | HPN | P05981 | 3/20 | 0.41 |
| ▸ | PGR | P06401 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21256820 | 0.84 | HPN (0.38) | RAB9ANPC1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL28752553 | 0.79 | HPN (0.59) | SMN1; SMN2POLBMAPTCYP1A2CYP2C19 | |
| SCHEMBL20684206 | 0.76 | RAB9A (0.46) | RAB9ANPC1EPHX1SMN1; SMN2POLB | |
| SCHEMBL28507028 | 0.72 | TSHR (0.51) | RAB9ANPC1EPHX1SMN1; SMN2POLB | |
| SCHEMBL28501678 | 0.71 | METAP2 (0.47) | RAB9ANPC1EPHX1SMN1; SMN2POLB | |
| SCHEMBL30445209 | 0.71 | HPN (0.52) | RAB9ANPC1EPHX1SMN1; SMN2POLB | |
| SCHEMBL17190162 | 0.70 | SHBG (0.41) | EPHX1SMN1; SMN2MAPTP2RX7 | |
| SCHEMBL9597796 | 0.70 | SHBG (0.41) | EPHX1SMN1; SMN2MAPTP2RX7 | |
| SCHEMBL4649302 | 0.70 | TSHR (0.46) | RAB9ANPC1EPHX1SMN1; SMN2MAPT | |
| SCHEMBL6715376 | 0.70 | HTR1E (0.62) | RAB9ANPC1EPHX1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767316-B2 | Non-fused thiophene derivatives and their uses | ENYO PHARMA (FR) | 2023-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11767316-B2 | Non-fused thiophene derivatives and their uses | FTH1, SLC40A1, FECH | RAB9A 1953/4885NPC1 320/4885EPHX1 2705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.