Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 4/20 | 0.59 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.59 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.59 |
| ▸ | PLAU | P00749 | 1/20 | 0.59 |
| ▸ | NOS3 | P29474 | 2/20 | 0.46 |
| ▸ | NOS1 | P29475 | 2/20 | 0.46 |
| ▸ | NOS2 | P35228 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1851528 | 0.81 | ADRA2A (0.50) | ADRA2AADRA2BADRA2CPLAUNOS3 | |
| SCHEMBL10841156 | 0.79 | ALDH1A1 (0.50) | ADRA2AADRA2BADRA2CPLAUNOS3 | |
| SCHEMBL10841472 | 0.76 | KMT2A (0.48) | ADRA2AADRA2BADRA2CPLAUMAOA | |
| SCHEMBL3536341 | 0.75 | ADRA2A (0.44) | ADRA2AADRA2BADRA2CPLAUNOS3 | |
| SCHEMBL2215019 | 0.75 | NOS3 (0.46) | ADRA2AADRA2BADRA2CPLAUNOS3 | |
| SCHEMBL2226462 | 0.74 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CPLAUNOS3 | |
| SCHEMBL5970257 | 0.73 | ADRA2A (0.43) | ADRA2AADRA2BADRA2CPLAUMAOA | |
| SCHEMBL6156050 | 0.73 | CES2 (0.39) | ADRA2AADRA2BADRA2CPLAUCES2 | |
| SCHEMBL4021935 | 0.71 | ADRA2A (0.70) | ADRA2AADRA2BADRA2CPLAUNOS3 | |
| SCHEMBL1703431 | 0.71 | ADRA2A (0.70) | ADRA2AADRA2BADRA2CPLAUNOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 288 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090163480-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | DR. KARL THOMAE GMBH (DE) | 2009-06-25 | — | — | US | claimed |
| US-20040214819-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | DR. KARL THOMAE GMBH (DE) | 2004-10-28 | — | — | US | claimed |
| EP-1440976-A1 | Modified aminoacids, pharmaceuticals containing these compounds and method for their production | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2004-07-28 | — | — | EP | claimed |
| US-20030069231-A1 | Modified aminoacids, pharmaceuticals containing these compounds and method for their production | RUDOLF KLAUS (DE) | 2003-04-10 | — | — | US | claimed |
| US-20010036946-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | RUDOLF KLAUS (DE) | 2001-11-01 | — | — | US | claimed |
| CN-113241478-A | Electrolyte solution, electrochemical device, and electricity-consuming apparatus | 宁德新能源科技有限公司 | 2021-08-10 | — | — | CN | disclosed |
| US-9988373-B2 | Nitrogen-containing six-membered cyclic derivatives and pharmaceutical composition comprising the same | SHIONOGI & CO., LTD. (JP) | 2018-06-05 | — | — | US | disclosed |
| US-9882072-B2 | Solar cell and transparent electrode | Konica Minolta, Inc. (JP) | 2018-01-30 | — | — | US | disclosed |
| EP-3093898-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE, LIGHTING DEVICE AND DISPLAY DEVICE | Konica Minolta Holdings, Inc. (JP) | 2016-11-16 | — | — | EP | disclosed |
| EP-2001065-B1 | ORGANIC ELECTROLUMINESCENT DEVICE, ILLUMINATING DEVICE AND DISPLAY DEVICE | KONICA MINOLTA HOLDINGS INC (JP) | 2016-11-09 | — | — | EP | disclosed |
| US-20160318916-A1 | NITROGEN-CONTAINING SIX-MEMBERED CYCLIC DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | SHIONOGI & CO., LTD. (JP) | 2016-11-03 | — | — | US | disclosed |
| US-9202636-B2 | Photoelectric conversion element and dye-sensitized solar cell | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2015-12-01 | — | — | US | disclosed |
| EP-1136877-A2 | Photothermographic material | KONICA CORPORATION (JP) | 2001-09-26 | — | — | EP | disclosed |
| US-5891614-A | FORMING HALOGEN COMPOSITION GAP FACES AT TIME OF NUCLEATION TO PRODUCE TABULAR GRAINS | FUJI PHOTO FILM CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| US-5780209-A | Processing of photographic silver halide photosensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1998-07-14 | — | — | US | disclosed |
| US-5667960-A | VINYL SULFONE DERIVATIVES | KONICA CORPORATION (JP) | 1997-09-16 | — | — | US | disclosed |
| EP-0752615-A2 | Method for hardening gelatin and silver halide photographic light sensitive materials employing the method | KONICA CORPORATION (JP) | 1997-01-08 | — | — | EP | disclosed |
| US-5582962-A | COLLOID LAYERS COMPRISING A DISPERSE DYE PARTICLES | KONICA CORPORATION (JP) | 1996-12-10 | — | — | US | disclosed |
| EP-0679935-A2 | Silver halide photographic light-sensitive material and the processing method thereof | KONICA CORPORATION (JP) | 1995-11-02 | — | — | EP | disclosed |
| US-5120637-A | Storage stability | FUJI PHOTO FILM CO., LTD. (JP) | 1992-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163480-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | PTMS, CHRM1, SRMS | ADRA2A 137/4885ADRA2B 157/4885ADRA2C 169/4885 |
| US-20160318916-A1 | NITROGEN-CONTAINING SIX-MEMBERED CYCLIC DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, NGLY1, C1R | ADRA2A 1139/4885ADRA2B 850/4885ADRA2C 353/4885 |
| US-20040214819-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | PTMS, SRMS, OPRM1 | ADRA2A 66/4885ADRA2B 106/4885ADRA2C 76/4885 |
| US-20030069231-A1 | Modified aminoacids, pharmaceuticals containing these compounds and method for their production | SLC1A5, NEFM, SRMS | ADRA2A 70/4885ADRA2B 78/4885ADRA2C 69/4885 |
| US-20010036946-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | PTMS, SRMS, OPRM1 | ADRA2A 66/4885ADRA2B 106/4885ADRA2C 76/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.