SCHEMBL20696643

SCHEMBL20696643

c1ccc2c(c1)-c1ccccc1C21c2cc3c(cc2-c2cc4c5c6ccccc6ccc5n(-c5cccc6c5sc5ccccc56)c4cc21)c1c2ccccc2ccc1n3-c1cccc2c1sc1ccccc12

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21264651 0.87 ALOX5 (0.33) ALOX5
SCHEMBL20199620 0.86 POLB (0.35)
SCHEMBL21397930 0.83 ALDH1A1 (0.33)
SCHEMBL20199646 0.82
SCHEMBL20199751 0.82 POLB (0.35)
SCHEMBL16373501 0.81 ALOX5 (0.38) ALOX5
SCHEMBL20199630 0.80 KDM4E (0.31)
SCHEMBL26476606 0.80 ALDH1A1 (0.30)
SCHEMBL25503193 0.79 ALOX5 (0.32) ALOX5
SCHEMBL26476604 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11917903-B2 Metal complexes UDC IRELAND LIMITED (IE) 2024-02-27 US disclosed
US-11917903-B2 Metal complexes UDC IRELAND LIMITED (IE) 2024-02-27 US disclosed
US-20230320191-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2023-10-05 US disclosed
US-11659763-B2 Metal complexes MERCK PATENT GMBH 2023-05-23 US disclosed
US-11535640-B2 Metal complexes MERCK PATENT GMBH (DE) 2022-12-27 US disclosed
US-11322696-B2 Metal complexes MERCK PATENT GMBH (DE) 2022-05-03 US disclosed
US-11145828-B2 Metal complexes MERCK PATENT GMBH (DE) 2021-10-12 US disclosed
US-11136343-B2 Binuclear metal complexes for use as emitters in organic electroluminescent devices MERCK PATENT GMBH (DE) 2021-10-05 US disclosed
US-20210175441-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2021-06-10 US disclosed
EP-3658564-B1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2021-05-19 EP disclosed
US-20210111345-A1 METAL COMPLEXES UDC IRELAND LIMITED (IE) 2021-04-15 US disclosed
EP-3507294-B1 BINUCLEAR AND TRINUCLEAR METAL COMPLEXES COMPOSED OF TWO INTER-LINKED TRIPODAL HEXADENTATE LIGANDS FOR USE IN ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-02-24 EP disclosed
US-20200207794-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2020-07-02 US disclosed
US-20200052213-A1 BINUCLEAR METAL COMPLEXES AND ELECTRONIC DEVICES, IN PARTICULAR ORGANIC ELECTROLUMINESCENT DEVICES CONTAINING SAID METAL COMPLEXES MERCK PATENT GMBH (DE) 2020-02-13 US disclosed
WO-2019179909-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2019-09-26 WO disclosed
WO-2019158453-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2019-08-22 WO disclosed
US-20190252628-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2019-08-15 US disclosed
WO-2019115423-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2019-06-20 WO disclosed
WO-2019020538-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2019-01-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11145828-B2 Metal complexes AP1M1, AP2M1, AP3M1 ALOX5 3754/4885
US-20190252628-A1 METAL COMPLEXES AP1M1, AP2M1, AP3M1 ALOX5 3754/4885
US-20230320191-A1 METAL COMPLEXES IMMT, MCU, SOD1 ALOX5 3289/4885
US-20210111345-A1 METAL COMPLEXES NCLN, BICRA, AP3M1 ALOX5 4255/4885
US-20210175441-A1 METAL COMPLEXES IMMT, MCU, SOD1 ALOX5 3289/4885
US-20200207794-A1 METAL COMPLEXES IMMT, MCU, SOD1 ALOX5 3289/4885
US-11322696-B2 Metal complexes AP1M1, AP3M1, AP2M1 ALOX5 3642/4885
US-11535640-B2 Metal complexes IMMT, MCU, SOD1 ALOX5 3289/4885
US-11659763-B2 Metal complexes IMMT, MCU, SOD1 ALOX5 3289/4885
US-11136343-B2 Binuclear metal complexes for use as emitters in organic electroluminescent devices AP2M1, MCU, AP3M1 ALOX5 3839/4885
US-20200052213-A1 BINUCLEAR METAL COMPLEXES AND ELECTRONIC DEVICES, IN PARTICULAR ORGANIC ELECTROLUMINESCENT DEVICES CONTAINING SAID METAL COMPLEXES BICRA, NCLN, IMMT ALOX5 3622/4885
US-11917903-B2 Metal complexes NCLN, BICRA, AP3M1 ALOX5 4255/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.