Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 6/20 | 0.53 |
| ▸ | NOS1 | P29475 | 6/20 | 0.53 |
| ▸ | NOS2 | P35228 | 6/20 | 0.53 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22813662 | 0.77 | NOS1 (0.44) | NOS3NOS1NOS2HTR2CHTR2A | |
| SCHEMBL15628864 | 0.75 | NOS3 (0.45) | NOS3NOS1NOS2CHRNB2CHRNA4 | |
| SCHEMBL6643393 | 0.69 | NOS1 (1.00) | NOS3NOS1NOS2 | |
| SCHEMBL22742883 | 0.68 | NOS1 (0.71) | NOS3NOS1NOS2CHRNB2CHRNA4 | |
| SCHEMBL21980046 | 0.64 | CHRNB2 (0.46) | NOS3NOS1NOS2CHRNB2CHRNA4 | |
| SCHEMBL25825971 | 0.64 | NOS3 (0.42) | NOS3NOS1NOS2CHRNB2CHRNA4 | |
| SCHEMBL25795661 | 0.63 | CHRNB2 (0.44) | NOS3NOS1NOS2CHRNB2CHRNA4 | |
| SCHEMBL22035375 | 0.63 | CHRNB2 (0.44) | NOS3NOS1NOS2CHRNB2CHRNA4 | |
| SCHEMBL22036440 | 0.63 | CHRNB2 (0.44) | NOS3NOS1NOS2CHRNB2CHRNA4 | |
| SCHEMBL27053456 | 0.63 | CHRNB2 (0.44) | NOS3NOS1NOS2CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3438095-A1 | PYRIDAZINONE-TYPE COMPOUND OR SALT THEREOF, AND HERBICIDE COMPRISING SAME | Ishihara Sangyo Kaisha, Ltd. (JP) | 2019-02-06 | — | — | EP | disclosed |