Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 3/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | CTSA | P10619 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23604021 | 0.79 | GRM5 (0.58) | IDO1CLK4GRM5 | |
| SCHEMBL3266995 | 0.79 | IDO1 (0.51) | XDHCTSSCTSKIDO1CLK4 | |
| SCHEMBL10431256 | 0.78 | GABRA1 (0.59) | XDHCTSSCTSKIDO1CLK4 | |
| SCHEMBL25900264 | 0.78 | GRM5 (0.50) | XDHCTSSCTSKIDO1CLK4 | |
| SCHEMBL23948695 | 0.77 | CTSS (0.46) | CTSSCTSKADORA2A | |
| SCHEMBL9792980 | 0.77 | CTSS (0.62) | XDHCTSSCTSKIDO1CLK4 | |
| SCHEMBL19531877 | 0.76 | KDM5A (0.46) | XDHCTSSCTSKCLK4GRM5 | |
| SCHEMBL2609332 | 0.76 | KMT2A (0.60) | ADORA2AADORA2BADORA1 | |
| SCHEMBL2609328 | 0.76 | CNR2 (0.44) | IDO1MAOBHSD11B1 | |
| SCHEMBL901316 | 0.76 | ASIC3 (0.56) | XDHCTSSCTSKIDO1CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210179636-A1 | ANTIBACTERIAL COMPOUNDS | REDX PHARMA PLC (GB) | 2021-06-17 | — | — | US | disclosed |
| US-20190055266-A1 | HETEROCYCLIC COMPOUNDS, IN PARTICULAR 2-OXO-4,4,5,5,6,6,7,7-OCTAHYDROBENZOXAZOLE DERIVATIVES, AND THEIR USE AS ANTIBACTERIAL COMPOUNDS | REDX PHARMA PLC (GB) | 2019-02-21 | — | — | US | disclosed |
| US-20190040083-A1 | ANTIBACTERIAL COMPOUNDS | REDX PHARMA PLC (GB) | 2019-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190040083-A1 | ANTIBACTERIAL COMPOUNDS | OXA1L, SYMPK, TBCD | XDH 428/4885CTSS 1150/4885CTSK 196/4885 |
| US-20190055266-A1 | HETEROCYCLIC COMPOUNDS, IN PARTICULAR 2-OXO-4,4,5,5,6,6,7,7-OCTAHYDROBENZOXAZOLE DERIVATIVES, AND THEIR USE AS ANTIBACTERIAL COMPOUNDS | OXA1L, OGFOD1, OCIAD2 | XDH 18/4885CTSS 3597/4885CTSK 1177/4885 |
| US-20210179636-A1 | ANTIBACTERIAL COMPOUNDS | OXA1L, SYMPK, TBCD | XDH 428/4885CTSS 1150/4885CTSK 196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.