Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | GBA1 | P04062 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16404773 | 0.79 | HDAC6 (0.67) | POLBKMT2AHDAC2HDAC8HDAC6 | |
| SCHEMBL17372930 | 0.76 | SMN1; SMN2 (0.68) | POLBKMT2ACYP19A1LMNAALDH1A1 | |
| SCHEMBL22234244 | 0.72 | GBA1 (0.57) | POLBKMT2AGBA1CYP19A1LMNA | |
| SCHEMBL4661757 | 0.71 | CYP19A1 (0.71) | KMT2ACYP19A1LMNASMN1; SMN2CXCR4 | |
| SCHEMBL17101693 | 0.70 | CA1 (0.49) | POLBKMT2AGBA1CYP19A1HDAC2 | |
| SCHEMBL7410831 | 0.70 | ITGB1 (0.63) | LMNAALDH1A1SMN1; SMN2CXCR4CA1 | |
| SCHEMBL9941756 | 0.70 | ALDH1A1 (0.69) | POLBKMT2ALMNAALDH1A1HTT | |
| SCHEMBL17101744 | 0.70 | POLB (0.54) | POLBKMT2AGBA1CYP19A1HDAC2 | |
| SCHEMBL25213296 | 0.69 | POLB (0.50) | POLBKMT2AGBA1CYP19A1LMNA | |
| SCHEMBL25223211 | 0.69 | POLB (0.53) | POLBKMT2AGBA1CYP19A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3022173-B1 | COMPOUNDS FOR THE TREATMENT AND/OR PREVENTION OF PARASITIC DISEASES AND METHOD OF PRODUCTION THEREOF | INSTITUT DE RECH POUR LE DEVELOPPEMENT I R D (FR) | 2019-02-20 | — | — | EP | disclosed |
| US-20190040004-A1 | NEW COMPOUNDS FOR THE TREATMENT AND/OR PREVENTION OF PARASITIC DISEASES AND METHOD OF PRODUCTION OF THEREOF | UNIVERSITE DE MONTPELLIER (FR) | 2019-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190040004-A1 | NEW COMPOUNDS FOR THE TREATMENT AND/OR PREVENTION OF PARASITIC DISEASES AND METHOD OF PRODUCTION OF THEREOF | PIGO, TTPA, TST | POLB 3694/4885KMT2A 2579/4885GBA1 140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.