Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 2/20 | 0.40 |
| ▸ | JAK1 | P23458 | 2/20 | 0.40 |
| ▸ | TYK2 | P29597 | 2/20 | 0.40 |
| ▸ | JAK3 | P52333 | 2/20 | 0.40 |
| ▸ | USP14 | P54578 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14109903 | 0.86 | CYP4F2 (0.54) | CYP4Z1MAPTACACBJAK2JAK1 | |
| SCHEMBL13268284 | 0.85 | RAB9A (0.51) | SMN1; SMN2NPC1PKMNFKB1RAB9A | |
| SCHEMBL2503936 | 0.80 | CYP4Z1 (0.50) | MAOBTBXAS1CYP4Z1SMN1; SMN2NPC1 | |
| SCHEMBL14677326 | 0.78 | MAOB (0.46) | MAOBTBXAS1CYP4Z1SMN1; SMN2NPC1 | |
| SCHEMBL31637608 | 0.78 | MAOB (0.46) | MAOBTBXAS1CYP4Z1SMN1; SMN2NPC1 | |
| SCHEMBL2769760 | 0.78 | TBXAS1 (0.43) | MAOBTBXAS1CYP4Z1SMN1; SMN2NPC1 | |
| SCHEMBL23021014 | 0.78 | GABRP (0.56) | NFKB1MAPTTSHRPARP14AR | |
| SCHEMBL25401317 | 0.78 | MAOB (0.47) | MAOBTBXAS1CYP4Z1SMN1; SMN2NPC1 | |
| SCHEMBL23149605 | 0.77 | ALDH1A1 (0.43) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL20943271 | 0.77 | ACACB (0.41) | SMN1; SMN2PKMNFKB1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3447058-B1 | NOVEL BROAD-SPECTRUM BETA-LACTAMASE INHIBITOR | WUHAN VISION PHARMACEUTICAL TECH CO LTD (CN) | 2023-10-11 | — | — | EP | disclosed |
| CN-107522634-B | Biaryl urea carboxylic acid derivative or salt thereof, and preparation method and application thereof | 复旦大学 | 2020-09-01 | — | — | CN | disclosed |
| US-10479805-B2 | Beta-lactamase inhibitor | WUHAN VISION PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2019-11-19 | — | — | US | disclosed |
| US-20190048027-A1 | BETA-LACTAMASE INHIBITOR | WUHAN VISION PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2019-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190048027-A1 | BETA-LACTAMASE INHIBITOR | ALPI, MGAM, LCT | MAOB 66/4885TBXAS1 1723/4885CYP4Z1 1011/4885 |
| US-10479805-B2 | Beta-lactamase inhibitor | ALPI, MGAM, LCT | MAOB 66/4885TBXAS1 1723/4885CYP4Z1 1011/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.