SCHEMBL20735129

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20735229	0.82	ALDH1A1 (0.51)	RAB9ASMN1; SMN2ERN1ALDH1A1KDM4E
	SCHEMBL23680127	0.78	ALDH1A1 (0.46)	RAB9ASMN1; SMN2NPC1TP53TSHR
	SCHEMBL20735042	0.76	PRMT1 (0.50)	ERN1ALDH1A1KDM4EHSD17B10ALOX15
	SCHEMBL23340349	0.76	RAB9A (0.46)	RAB9ASMN1; SMN2HIF1ANPC1TP53
	SCHEMBL21677922	0.74	ALDH1A1 (0.42)	RAB9ASMN1; SMN2NPC1TP53TSHR
	SCHEMBL20735178	0.73	ALDH1A1 (0.50)	SMN1; SMN2TP53CYP2C9ALDH1A1KDM4E
	SCHEMBL21846070	0.72	KDM4E (0.54)	RAB9ASMN1; SMN2NPC1TP53TSHR
	SCHEMBL23790146	0.72	KDM4E (0.54)	RAB9ASMN1; SMN2NPC1TP53TSHR
	SCHEMBL20735130	0.71	ALDH1A1 (0.59)	RAB9ASMN1; SMN2ALDH1A1KDM4EMAPT
	SCHEMBL11750641	0.70	RAB9A (0.57)	RAB9ASMN1; SMN2HIF1ANPC1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.