SCHEMBL20735206

SCHEMBL20735206

CN1C(=O)c2cccc3c(-c4ccc(-c5ccc6c7c(cccc57)C(=O)N(C)C6O)c5ccccc45)ccc(c23)C1=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 9/20 0.52
▸ KMT2A Q03164 8/20 0.52
▸ KDM4E B2RXH2 7/20 0.52
▸ MEN1 O00255 6/20 0.52
▸ USP2 O75604 5/20 0.52
▸ KEAP1 Q14145 3/20 0.52
▸ NFE2L2 Q16236 3/20 0.52
▸ ATM Q13315 1/20 0.52
▸ HPGD P15428 1/20 0.52
▸ POLB P06746 5/20 0.50
▸ PRMT1 Q99873 1/20 0.50
▸ TDP1 Q9NUW8 2/20 0.41
▸ RECQL P46063 2/20 0.41
▸ APOBEC3A P31941 1/20 0.41
▸ CASP6 P55212 1/20 0.41
▸ APOBEC3G Q9HC16 1/20 0.41
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ MAPT P10636 5/20 0.41
▸ NPC1 O15118 1/20 0.41
▸ RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21235823 0.84 MEN1 (0.42) ALDH1A1KMT2AKDM4EMEN1USP2
SCHEMBL20735127 0.83 KMT2A (0.71) ALDH1A1KMT2AKDM4EMEN1USP2
SCHEMBL12869500 0.82 KMT2A (0.73) ALDH1A1KMT2AKDM4EMEN1USP2
SCHEMBL22872422 0.81 MEN1 (0.42) ALDH1A1KMT2AKDM4EMEN1USP2
SCHEMBL20739760 0.80 ALOX5 (0.44) ALDH1A1KMT2AKDM4EMEN1USP2
SCHEMBL20735200 0.78 CYP11B1 (0.47) ALDH1A1KMT2AKDM4EMEN1USP2
SCHEMBL20735091 0.77 KMT2A (0.63) ALDH1A1KMT2AKDM4EMEN1USP2
SCHEMBL23340523 0.77 ADK (0.36) ALDH1A1KMT2AKDM4EMEN1USP2
SCHEMBL19421020 0.77 PRMT1 (0.59) ALDH1A1KMT2AKDM4EMEN1USP2
SCHEMBL20735098 0.76 KMT2A (0.61) ALDH1A1KMT2AKDM4EMEN1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10381596-B2 Organic light-emitting display apparatus with an encapsulation unit SAMSUNG DISPLAY CO., LTD. (KR) 2019-08-13 — — US disclosed
US-20190051860-A1 ORGANIC LIGHT-EMITTING DISPLAY APPARATUS SAMSUNG DISPLAY CO., LTD. (KR) 2019-02-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190051860-A1 ORGANIC LIGHT-EMITTING DISPLAY APPARATUS ALDH1A1, AOX1, ALDH1A2 ALDH1A1 1/4885KMT2A 3171/4885KDM4E 4393/4885
US-10381596-B2 Organic light-emitting display apparatus with an encapsulation unit ALDH1A1, AOX1, AMY1A ALDH1A1 1/4885KMT2A 3160/4885KDM4E 4278/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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