Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 3/20 | 0.32 |
| ▸ | CCND1 | P24385 | 3/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.30 |
| ▸ | CA9 | Q16790 | 2/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.30 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.30 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL137023 | 0.71 | CA12 (0.39) | CDK4CCND1CYP2A6ALOX12KMT2A | |
| SCHEMBL3849038 | 0.71 | CA12 (0.34) | CDK4CCND1CYP2A6ALOX12KMT2A | |
| SCHEMBL650735 | 0.71 | NOS2 (0.34) | CDK4CCND1CYP2A6ALOX12CA12 | |
| SCHEMBL2073401 | 0.71 | CDK4 (0.32) | CDK4CCND1CYP2A6ALOX12CA12 | |
| SCHEMBL570353 | 0.71 | CDK4 (0.32) | CDK4CCND1CYP2A6ALOX12CA12 | |
| SCHEMBL127255 | 0.71 | DAO (0.35) | CDK4CCND1CYP2A6ALOX12KMT2A | |
| SCHEMBL718221 | 0.68 | KDM4E (0.37) | CDK4CCND1KMT2AALDH1A1 | |
| SCHEMBL2071020 | 0.67 | SMN1; SMN2 (0.38) | CYP2A6CA12CA9BRD4BRPF1 | |
| SCHEMBL4724354 | 0.67 | SLC6A2 (0.35) | SLC6A2CA12CA9BRD4BRPF1 | |
| SCHEMBL5497336 | 0.67 | CYP1A2 (0.35) | CDK4CCND1KMT2ACA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166041-A | 2-heteroaryl and 2-heterocyclic benzoxazoles as PDE IV inhibitors for the treatment of asthma | EURO-CELTIQUE, S.A. (LU) | 2000-12-26 | — | — | US | claimed |
| US-20200384111-A1 | MODIFIED CARBON NANOMATERIAL, NANOCLUSTER, SUBSTANCE DELIVERY CARRIER, AND PHARMACEUTICAL COMPOSITION | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2020-12-10 | — | — | US | disclosed |
| EP-3725331-A1 | MODIFIED CARBON NANOMATERIAL, NANOCLUSTER, SUBSTANCE DELIVERY CARRIER, AND PHARMACEUTICAL COMPOSITION | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2020-10-21 | — | — | EP | disclosed |
| EP-2894685-B1 | BENZOTHIENOBENZOTHIOPHENE DERIVATIVE, ORGANIC SEMICONDUCTOR MATERIAL, AND ORGANIC TRANSISTOR | DAINIPPON INK & CHEMICALS (JP) | 2018-10-31 | — | — | EP | disclosed |
| US-20180248131-A1 | ORGANIC COMPOUND, METHOD FOR PREPARING SAME, ORGANIC SEMICONDUCTOR MATERIAL CONTAINING SAME, AND ORGANIC TRANSISTOR CONTAINING SAME | DIC CORPORATION (JP) | 2018-08-30 | — | — | US | disclosed |
| EP-3342769-A1 | ORGANIC COMPOUND, METHOD FOR MANUFACTURING SAME, ORGANIC SEMICONDUCTOR MATERIAL CONTAINING SAME, AND ORGANIC TRANSISTOR CONTAINING SAME | DIC Corporation (JP) | 2018-07-04 | — | — | EP | disclosed |
| US-9490433-B2 | Benzothienobenzothiophene derivative, organic semiconductor material, and organic transistor | DIC CORPORATION (JP) | 2016-11-08 | — | — | US | disclosed |
| US-20150228913-A1 | BENZOTHIENOBENZOTHIOPHENE DERIVATIVE, ORGANIC SEMICONDUCTOR MATERIAL, AND ORGANIC TRANSISTOR | DIC CORPORATION (JP) | 2015-08-13 | — | — | US | disclosed |
| EP-1976833-B1 | HETEROCYCLE SUBSTITUTED AMIDE AND SULFUR AMIDE DERIVATIVES AS HISTONE DEACETYLASE (HDAC) INHIBITORS | MSD ITALIA SRL (IT) | 2015-07-29 | — | — | EP | disclosed |
| EP-2894685-A1 | BENZOTHIENOBENZOTHIOPHENE DERIVATIVE, ORGANIC SEMICONDUCTOR MATERIAL, AND ORGANIC TRANSISTOR | DIC Corporation (JP) | 2015-07-15 | — | — | EP | disclosed |
| US-20020107272-A1 | Anti-HIV imidazolone derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 2002-08-08 | — | — | US | disclosed |
| WO-2002042279-A1 | IMIDAZOLONE DERIVATIVES FOR THE TREATMENT OF VIRAL DISEASES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-05-30 | — | — | WO | disclosed |
| US-6291464-B1 | POTENTIATION OF THE CHOLINERGIC ACTIVITY; THERAPEUTIC TREATMENT OF AMNESIA, DEMENTIA OR SENILE DEMENTIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-09-18 | — | — | US | disclosed |
| EP-0968201-A2 | NEW AMINOPIPERAZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-01-05 | — | — | EP | disclosed |
| EP-0898569-A1 | PIPERIDINES AND PYRROLIDINES | MERCK PATENT GmbH (DE) | 1999-03-03 | — | — | EP | disclosed |
| US-5801147-A | ADMINISTERING A POLYPEPTIDE AS AMIDE, ESTER OR SALT FOR NERVE ACTIVATION AND GASTRIC INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-01 | — | — | US | disclosed |
| WO-1998035951-A2 | NEW AMINOPIPERAZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-08-20 | — | — | WO | disclosed |
| WO-1997040038-A1 | PIPERIDINES AND PYRROLIDINES | MERCK PATENT GMBH (DE) | 1997-10-30 | — | — | WO | disclosed |
| US-5623050-A | NERVE ACTIVATING AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-04-22 | — | — | US | disclosed |
| EP-0529487-A2 | PACAP derivatives having c-AMP producing activity | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-03-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020107272-A1 | Anti-HIV imidazolone derivatives | EIF2AK2, IMPDH1, POLR2E | CDK4 80/4885CCND1 622/4885CYP2A6 1283/4885 |
| US-20180248131-A1 | ORGANIC COMPOUND, METHOD FOR PREPARING SAME, ORGANIC SEMICONDUCTOR MATERIAL CONTAINING SAME, AND ORGANIC TRANSISTOR CONTAINING SAME | TST, SOAT1, SOAT2 | CDK4 1769/4885CCND1 352/4885CYP2A6 2156/4885 |
| US-20150228913-A1 | BENZOTHIENOBENZOTHIOPHENE DERIVATIVE, ORGANIC SEMICONDUCTOR MATERIAL, AND ORGANIC TRANSISTOR | TST, TPST2, TPR | CDK4 845/4885CCND1 814/4885CYP2A6 2445/4885 |
| US-20200384111-A1 | MODIFIED CARBON NANOMATERIAL, NANOCLUSTER, SUBSTANCE DELIVERY CARRIER, AND PHARMACEUTICAL COMPOSITION | CHRM1, SLC67A1, NPSR1 | CDK4 2478/4885CCND1 497/4885CYP2A6 252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.