Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.44 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | RORA | P35398 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | RORB | Q92753 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18067919 | 0.76 | MEN1 (0.42) | PLA2G4ASKP2OXER1RORARORC | |
| SCHEMBL1315631 | 0.75 | HTR2A (0.42) | TLR8PLA2G4AOXER1HTR2ARORA | |
| SCHEMBL12348264 | 0.74 | OXER1 (0.53) | OXER1HTR2ARORARORCRORB | |
| SCHEMBL13616802 | 0.73 | RORA (0.59) | HTR2ARORARORCRORBKDM4E | |
| SCHEMBL6563401 | 0.73 | BDKRB2 (0.55) | TLR8HTR2AKDM4ELMNAALDH1A1 | |
| SCHEMBL16894438 | 0.73 | MEN1 (0.42) | PLA2G4ASKP2OXER1RORARORC | |
| SCHEMBL27525288 | 0.73 | OXER1 (0.46) | PLA2G4AOXER1RORARORCRORB | |
| SCHEMBL14402843 | 0.72 | CTNNB1 (0.56) | TLR8PLA2G4AOXER1HTR2ARORA | |
| SCHEMBL28283584 | 0.72 | BRPF1 (0.46) | TLR8PLA2G4AOXER1MEN1KMT2A | |
| SCHEMBL11690859 | 0.72 | PTGS2 (0.57) | HTR2AKDM4ELMNAALDH1A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3444242-A2 | NOVEL BENZOPYRAN KINASE MODULATORS | Rhizen Pharmaceuticals S.A. (CH) | 2019-02-20 | — | — | EP | disclosed |