Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12094406 | 0.87 | POLB (0.38) | KMT2AMEN1 | |
| SCHEMBL10475746 | 0.87 | ALOX15 (0.37) | KMT2AMEN1ALDH1A1KDM4ELMNA | |
| SCHEMBL18118469 | 0.87 | ALOX15 (0.37) | KMT2AMEN1ALDH1A1KDM4ELMNA | |
| SCHEMBL12906770 | 0.87 | ALOX15 (0.37) | KMT2AMEN1ALDH1A1KDM4ELMNA | |
| SCHEMBL15518427 | 0.85 | HSD17B10 (0.39) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL560792 | 0.85 | HSD17B10 (0.39) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL1241402 | 0.83 | GAA (0.41) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL30565785 | 0.83 | MGLL (0.31) | — | |
| SCHEMBL12092237 | 0.83 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL3700587 | 0.83 | PLA2G10 (0.38) | KMT2AMEN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2367576-B1 | METHOD FOR THE PRODUCTION OF SCAFFOLDS FOR TISSUE ENGINEERING, COMPRISING THE USE OF AN ANCHORING UNIT, AND SCAFFOLD PRODUCED THEREWITH | KONINKLIJKE PHILIPS NV (NL) | 2019-02-20 | — | — | EP | disclosed |