Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromoacetic Acid SCHEMBL5150463 | 0.91 | KMT2A (0.38) | GAAKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL17053358 | 0.87 | HSD17B10 (0.36) | KMT2AALDH1A1MEN1SMN1; SMN2CHRM2 | |
| SCHEMBL17057486 | 0.87 | HSD17B10 (0.36) | KMT2AALDH1A1MEN1SMN1; SMN2CHRM2 | |
| SCHEMBL560792 | 0.84 | HSD17B10 (0.39) | KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL15518427 | 0.84 | HSD17B10 (0.39) | KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL12906770 | 0.83 | ALOX15 (0.37) | GAAKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL10475746 | 0.83 | ALOX15 (0.37) | GAAKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL18118469 | 0.83 | ALOX15 (0.37) | GAAKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL20750016 | 0.83 | KMT2A (0.41) | GAAKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL1241407 | 0.83 | CHRM5 (0.39) | KMT2AMEN1CHRM5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8697604-B2 | Labeling agents for mass spectrometry comprising tertiary amines | ELECTROPHORETICS LIMITED (GB) | 2014-04-15 | — | — | US | disclosed |
| US-8679773-B2 | Kits pertaining to analyte determination | DH TECHNOLOGIES DEVELOPMENT PTE. LTD. (SG) | 2014-03-25 | — | — | US | disclosed |
| EP-2251334-B1 | Labeling reagents and labeled analytes | DH TECHNOLOGIES DEV PTE LTD (SG) | 2013-08-14 | — | — | EP | disclosed |
| EP-1606623-B1 | LABELLING AGENTS FOR MASS SPECTROMETRY COMPRISING TERTIARY AMINES | ELECTROPHORETICS LTD (GB) | 2013-05-22 | — | — | EP | disclosed |
| EP-1606623-B1 | LABELLING AGENTS FOR MASS SPECTROMETRY COMPRISING TERTIARY AMINES | ELECTROPHORETICS LTD (GB) | 2013-05-22 | — | — | EP | disclosed |
| US-8273706-B2 | Isobarically labeled analytes and fragment ions derived therefrom | DH TECHNOLOGIES DEVELOPMENT PTE. LTD. (SG) | 2012-09-25 | — | — | US | disclosed |
| US-20110217720-A1 | Compositions and Kits Pertaining to Analyte Determination | PAPPIN DARRYL J C | 2011-09-08 | — | — | US | disclosed |
| EP-1588145-B1 | METHODS, MIXTURES, KITS AND COMPOSITIONS PERTAINING TO ANALYTE DETERMINATION | LIFE TECHNOLOGIES CORP (US) | 2011-07-06 | — | — | EP | disclosed |
| US-7947513-B2 | Sets and compositions pertaining to analyte determination | DH Technologies Ptd. Ltd. (SG) | 2011-05-24 | — | — | US | disclosed |
| US-7910059-B2 | For the determination of an analyte or analytes such as proteins, peptides, nucleic acids, carbohydrates, lipids, steroids and small molecules by mass analysis | DH TECHNOLOGIES PTE. LTD. (SG) | 2011-03-22 | — | — | US | disclosed |
| US-20060105416-A1 | Methods, compositions and kits pertaining to analyte determination | APPLERA CORPORATION (US) | 2006-05-18 | — | — | US | disclosed |
| EP-1606623-A2 | LABELLING AGENTS FOR MASS SPECTROMETRY COMPRISING TERTIARY AMINES | Xzillion GmbH & CO.KG (DE) | 2005-12-21 | — | — | EP | disclosed |
| EP-1588145-A2 | METHODS, MIXTURES, KITS AND COMPOSITIONS PERTAINING TO ANALYTE DETERMINATION | Applera Corporation (US) | 2005-10-26 | — | — | EP | disclosed |
| WO-2005068446-A1 | LABELING REAGENTS, LABELED ANALYTES, INCLUDING MIXTURES THEREOF, AND FRAGMENT IONS DERIVED THEREFROM AND METHODS FOR THE ANALYSIS THEREOF | APPLERA CORPORATION (US) | 2005-07-28 | — | — | WO | disclosed |
| US-20050148087-A1 | Isobarically labeled analytes and fragment ions derived therefrom | APPLERA CORPORATION | 2005-07-07 | — | — | US | disclosed |
| US-20040219685-A1 | Methods and mixtures pertaining to analyte determination using electrophilic labeling reagents | APPLERA CORPORATION | 2004-11-04 | — | — | US | disclosed |
| US-20040220412-A1 | Compositions and kits pertaining to analyte determination | APPLE CORPORATION | 2004-11-04 | — | — | US | disclosed |
| US-20040219686-A1 | Methods and mixtures pertaining to analyte determination | APPLIED BIOSYSTEMS, LLC | 2004-11-04 | — | — | US | disclosed |
| WO-2004086050-A2 | LABELLING AGENTS FOR MASS SPECTROMETRY COMPRISING TERTIARY AMINES | XZILLION GMBH & CO. KG (DE) | 2004-10-07 | — | — | WO | disclosed |
| WO-2004070352-A2 | METHODS, MIXTURES, KITS AND COMPOSITIONS PERTAINING TO ANALYTE DETERMINATION | APPLERA CORPORATION (US) | 2004-08-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060105416-A1 | Methods, compositions and kits pertaining to analyte determination | SRMS, SHBG, KLK3 | GAA 927/4885KMT2A 2527/4885ALDH1A1 320/4885 |
| US-20050148087-A1 | Isobarically labeled analytes and fragment ions derived therefrom | KLK3, SRMS, PTMS | GAA 1405/4885KMT2A 4071/4885ALDH1A1 538/4885 |
| US-20040220412-A1 | Compositions and kits pertaining to analyte determination | KLK3, SRMS, SHBG | GAA 1012/4885KMT2A 3232/4885ALDH1A1 263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.