Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GRK2 | P25098 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | QPCT | Q16769 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | DUSP22 | Q9NRW4 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | RGS4 | P49798 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890190 | 0.81 | KLKB1 (0.53) | NSD2POLBGRK2CASP6CTDSP1 | |
| SCHEMBL20760789 | 0.79 | RGS4 (0.40) | CA2RGS4MEN1KMT2A | |
| SCHEMBL22153147 | 0.76 | POLB (0.47) | POLBCYP2D6MEN1KMT2AGAA | |
| SCHEMBL18919417 | 0.76 | MGLL (0.53) | POLBRGS4MEN1KMT2A | |
| SCHEMBL6755043 | 0.76 | MGLL (0.62) | NSD2POLBGRK2CASP6CTDSP1 | |
| SCHEMBL1163961 | 0.76 | MGLL (0.50) | RGS4MEN1KMT2AGAATSHR | |
| Hydrochloric Acid SCHEMBL6753371 | 0.75 | MGLL (0.60) | NSD2POLBGRK2CASP6CTDSP1 | |
| Hydrazine SCHEMBL16908509 | 0.73 | MGLL (0.58) | NSD2POLBGRK2CASP6CTDSP1 | |
| SCHEMBL8889327 | 0.73 | KLKB1 (0.59) | NSD2POLBGRK2CASP6CTDSP1 | |
| SCHEMBL9725345 | 0.73 | FAAH (0.39) | POLBCA2RGS4LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190055195-A1 | Phenyl, bromo-maleimide as a coupling group for conjugation to sulfhydryl group | Immunwork Inc. (TW) | 2019-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190055195-A1 | Phenyl, bromo-maleimide as a coupling group for conjugation to sulfhydryl group | BRI3BP, CTH, BRD2 | NSD2 381/4885POLB 4437/4885GRK2 2857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.