Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.39 |
| ▸ | BAD | Q92934 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29333201 | 0.79 | ALDH1A1 (0.33) | POLBALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL20760459 | 0.76 | NSD2 (0.46) | POLBGAAKMT2AMEN1CYP2D6 | |
| SCHEMBL22153141 | 0.76 | TGM2 (0.44) | POLBALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL29333195 | 0.73 | POLB (0.39) | POLBALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL18919417 | 0.72 | MGLL (0.53) | POLBKMT2AMEN1TDP1PKM | |
| SCHEMBL20760789 | 0.71 | RGS4 (0.40) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL17114021 | 0.71 | POLB (0.71) | POLBALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL22152325 | 0.71 | RGS4 (0.44) | POLBALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL26623027 | 0.69 | ALDH1A1 (0.67) | POLBALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL7830939 | 0.69 | MGLL (0.53) | POLBALDH1A1GAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020125546-A1 | CONNECTOR FOR USE IN ANTIBODY MEDICAMENT CONJUGATE AND APPLICATIONS OF CONNECTOR | 荣昌生物制药（烟台）有限公司 | 2020-06-25 | — | — | WO | disclosed |