SCHEMBL2076110

SCHEMBL2076110

CC(C)(C)OC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)OC(C)(C)C

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSS P25774 6/20 0.67
CTSK P43235 5/20 0.67
LY96 Q9Y6Y9 1/20 0.56
CTSL P07711 1/20 0.53
CTSB P07858 1/20 0.53
ACE P12821 1/20 0.51
ITGB3 P05106 1/20 0.51
ITGA2B P08514 1/20 0.51
KLK5 Q9Y337 1/20 0.50
PPARA Q07869 2/20 0.49
MDM4 O15151 1/20 0.49
MDM2 Q00987 1/20 0.49
ITGA4 P13612 1/20 0.48
ITGB7 P26010 1/20 0.48
POLB P06746 1/20 0.47
MAPT P10636 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
PPARG P37231 1/20 0.47
KMT2A Q03164 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14405376 1.00 CTSS (0.67) CTSSCTSKLY96CTSLCTSB
SCHEMBL309644 1.00 CTSS (0.67) CTSSCTSKLY96CTSLCTSB
SCHEMBL539575 0.93 CTSS (0.66) CTSSCTSKLY96CTSLCTSB
SCHEMBL2574440 0.93 CTSS (0.66) CTSSCTSKLY96CTSLCTSB
SCHEMBL30374091 0.93 CTSS (0.66) CTSSCTSKLY96CTSLCTSB
SCHEMBL539574 0.93 CTSS (0.66) CTSSCTSKLY96CTSLCTSB
SCHEMBL7260689 0.91 CTSS (0.63) CTSSCTSKLY96CTSLCTSB
SCHEMBL920111 0.91 CTSS (0.63) CTSSCTSKLY96CTSLCTSB
SCHEMBL16470394 0.89 CTSS (0.62) CTSSCTSKLY96CTSLCTSB
SCHEMBL14884529 0.89 CTSS (0.62) CTSSCTSKLY96CTSLCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117777248-A Water-based solid phase synthesis method of multi-receptor agonist polypeptide Retatrutide 润辉生物技术(威海)有限公司 2024-03-29 CN claimed
WO-2026090272-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF DISEASE 2508 BIOSCIENCES LLC (US) 2026-04-30 WO disclosed
EP-4540267-B1 CYCLIC PEPTIDES FOR TRAPPING INTERLEUKIN-1 BETA MERCK SHARP & DOHME LLC (US) 2026-04-15 EP disclosed
US-20260092072-A1 INHIBITORS OF ALDOSE REDUCTASE BARCLAYS BANK PLC (GB) 2026-04-02 US disclosed
US-12528823-B2 Inhibitors of aldose reductase Applied Therapeutics, Inc. (US) 2026-01-20 US disclosed
EP-3604326-B1 PEPTIDE COMPOUND AND METHOD FOR PRODUCING SAME, COMPOSITION FOR SCREENING USE, AND METHOD FOR SELECTING PEPTIDE COMPOUND FUJIFILM CORP (JP) 2026-01-07 EP disclosed
WO-2025106386-A1 A CYCLIC PEPTIDE FOR TRAPPING INTERLEUKIN-1 BETA MERCK SHARP & DOHME LLC (US) 2025-05-22 WO disclosed
US-20250152658-A1 CYCLIC PEPTIDE FOR TRAPPING INTERLEUKIN-1 BETA MERCK SHARP & DOHME LLC (US) 2025-05-15 US disclosed
CN-119350471-B Tenipout peptide synthesis method 中肽生化有限公司 2025-04-25 CN disclosed
EP-4540267-A1 CYCLIC PEPTIDES FOR TRAPPING INTERLEUKIN-1 BETA Merck Sharp & Dohme LLC (US) 2025-04-23 EP disclosed
US-20100152456-A1 Intermediate compound for synthesis of viridiofungin a derivative CHUGAI SEIYAKU KABUSHIKI KAISHA 2010-06-17 US disclosed
US-20100152457-A1 Intermediate compound for synthesis of viridiofungin a derivative CHUGAI SEIYAKU KABUSHIKI KAISHA 2010-06-17 US disclosed
US-20100120686-A1 COMPOSITIONS CONTAINING, METHODS INVOLVING, AND USES OF NON-NATURAL AMINO ACIDS AND POLYPEPTIDES AMBRX, INC. (US) 2010-05-13 US disclosed
US-7638491-B2 Administering a polypeptide having an oxime-containing non-natural amino acid, from a translation system of: a polynucleotide comprising a selector codon encoding the polypeptide, a tRNA comprising the oxime-containing amino acid AMBRX, INC. (US) 2009-12-29 US disclosed
US-20080293950-A1 Production Process of Compound Having Anti-Hcv Action and Intermediate Thereof CHUGAI SEIYAKU KABUSHIKI KAISHA 2008-11-27 US disclosed
US-7385028-B2 Modified non-natural amino acid polypeptides typically include at least one oxime, carbonyl, dicarbonyl, and/or hydroxylamine group; therapeutic, diagnostic, and other biotechnology uses AMBRX, INC (US) 2008-06-10 US disclosed
US-7378446-B2 Compound having anti-HCV activity and process for producing the same CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2008-05-27 US disclosed
US-7378446-B2 Compound having anti-HCV activity and process for producing the same CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2008-05-27 US disclosed
US-7332571-B2 Non-natural amino acid polypeptides and modified non-natural amino acid polypeptides, therapeutic, diagnostic, and other biotechnology uses AMBRX, INC. (US) 2008-02-19 US disclosed
EP-1857456-A1 PROCESS FOR PRODUCING COMPOUND WITH ANTI-HCV POTENCY AND INTERMEDIATE FOR USE THEREIN CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2007-11-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100120686-A1 COMPOSITIONS CONTAINING, METHODS INVOLVING, AND USES OF NON-NATURAL AMINO ACIDS AND POLYPEPTIDES PTMS, DAO, DNPEP CTSS 3645/4885CTSK 2731/4885LY96 1035/4885
US-20100152457-A1 Intermediate compound for synthesis of viridiofungin a derivative ZC3HAV1, ZC3HAV1L, MAVS CTSS 2415/4885CTSK 1536/4885LY96 2253/4885
US-12528823-B2 Inhibitors of aldose reductase CBR1, AKR1C3, AKR1C2 CTSS 2388/4885CTSK 3066/4885LY96 2014/4885
US-20080293950-A1 Production Process of Compound Having Anti-Hcv Action and Intermediate Thereof HCCS, EIF2AK2, MAVS CTSS 2453/4885CTSK 1810/4885LY96 2394/4885
US-20100152456-A1 Intermediate compound for synthesis of viridiofungin a derivative ZC3HAV1, ZC3HAV1L, MAVS CTSS 2415/4885CTSK 1536/4885LY96 2253/4885
US-20260092072-A1 INHIBITORS OF ALDOSE REDUCTASE UGCG, CBR1, LIPG CTSS 1380/4885CTSK 2701/4885LY96 3650/4885
US-20250152658-A1 CYCLIC PEPTIDE FOR TRAPPING INTERLEUKIN-1 BETA IL1R1, IL1A, IL1B CTSS 1403/4885CTSK 1280/4885LY96 2578/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.