Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20765718 | 0.83 | ALDH1A1 (0.67) | ALDH1A1HPGDPOLBRAB9ASMN1; SMN2 | |
| SCHEMBL17468532 | 0.77 | HRH4 (0.62) | KMT2AMEN1ALDH1A1HPGDPOLB | |
| SCHEMBL31520485 | 0.77 | MEN1 (1.00) | KMT2AMEN1ALDH1A1POLBRAB9A | |
| SCHEMBL16598920 | 0.76 | MAOB (0.56) | KMT2AMEN1ALDH1A1HPGDPOLB | |
| SCHEMBL20765540 | 0.76 | ENPP2 (0.57) | ALDH1A1HPGDPOLBRAB9ASMN1; SMN2 | |
| SCHEMBL95734 | 0.74 | MEN1 (0.82) | KMT2AMEN1ALDH1A1POLBRAB9A | |
| SCHEMBL13290581 | 0.73 | AKR1C3 (0.56) | KMT2AMEN1ALDH1A1POLBPARP1 | |
| SCHEMBL6893687 | 0.71 | ALDH1A1 (0.79) | KMT2AMEN1ALDH1A1POLBRAB9A | |
| SCHEMBL20774926 | 0.71 | ALDH1A1 (0.50) | ALDH1A1HPGDPOLBRAB9ASMN1; SMN2 | |
| SCHEMBL8262960 | 0.70 | MEN1 (0.60) | KMT2AMEN1ALDH1A1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019038683-A1 | COMPOUNDS TARGETING TANDEM BRCT DOMAINS OF BRCA1, COMPOSITIONS AND METHODS THEREOF | INSTITUTE FOR STEM CELL BIOLOGY AND REGENERATIVE MEDICINE (IN) | 2019-02-28 | — | — | WO | claimed |