Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | TTR | P02766 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MMP14 | P50281 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11878475 | 0.95 | MAPT (0.61) | MAPTALDH1A1LMNAL3MBTL1ADORA2A | |
| SCHEMBL16224285 | 0.87 | MAPT (0.69) | MAPTALDH1A1LMNAL3MBTL1MEN1 | |
| SCHEMBL29568790 | 0.83 | MAPT (0.74) | MAPTALDH1A1LMNAL3MBTL1MEN1 | |
| SCHEMBL71118 | 0.83 | MAPT (0.74) | MAPTALDH1A1LMNAL3MBTL1MEN1 | |
| SCHEMBL1652930 | 0.81 | ALDH1A1 (0.57) | MAPTALDH1A1LMNAL3MBTL1MEN1 | |
| SCHEMBL308115 | 0.81 | ADORA2A (0.76) | MAPTALDH1A1LMNAL3MBTL1ADORA2A | |
| SCHEMBL8496259 | 0.80 | ALDH1A1 (0.59) | MAPTALDH1A1LMNAL3MBTL1MEN1 | |
| SCHEMBL27736815 | 0.79 | MAPT (0.59) | MAPTALDH1A1LMNAL3MBTL1MEN1 | |
| Methoxymethane SCHEMBL8415315 | 0.77 | MAPT (0.65) | MAPTALDH1A1LMNAL3MBTL1MEN1 | |
| SCHEMBL3453760 | 0.76 | MAPT (0.66) | MAPTALDH1A1LMNAL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9563138-B2 | Electrophotographic photoreceptor, process cartridge, and image forming apparatus | FUJI XEROX CO., LTD. (JP) | 2017-02-07 | — | — | US | disclosed |
| US-20160238955-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS | FUJIFILM BUSINESS INNOVATION CORP. (JP) | 2016-08-18 | — | — | US | disclosed |
| US-9335644-B2 | Electron transport material, electrophotographic photoreceptor, process cartridge, and image forming apparatus | FUJI XEROX CO., LTD. (JP) | 2016-05-10 | — | — | US | disclosed |
| US-20160085164-A1 | ELECTRON TRANSPORT MATERIAL, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS | FUJIFILM BUSINESS INNOVATION CORP. (JP) | 2016-03-24 | — | — | US | disclosed |
| US-8163750-B2 | Fluorene derivatives, compositions containing the same and use thereof as inhibitors of the protein chaperone HSP 90 | SANOFI-AVENTIS (FR) | 2012-04-24 | — | — | US | disclosed |
| US-20100130503-A1 | NEW FLUORENE DERIVATIVES, COMPOSITIONS CONTAINING THE SAME AND USE THEREOF AS INHIBITORS OF THE PROTEIN CHAPERONE HSP 90 | SANOFI-AVENTIS (FR) | 2010-05-27 | — | — | US | disclosed |
| US-7674795-B2 | Fluorene derivatives, composition containing said derivatives and the use thereof | AVENTIS PHARMA SA (FR) | 2010-03-09 | — | — | US | disclosed |
| US-20080153837-A1 | Novel Fluorene Derivatives, Composition Containing Said Derivatives and the Use Thereof | AVENTIS PHARMA S.A. (FR) | 2008-06-26 | — | — | US | disclosed |
| US-20070219197-A1 | Pyridyl alkene and pyridyl alkine- acid amides as cytostatics and immuno-suppressives | ASTELLAS PHARMA GMBH (DE) | 2007-09-20 | — | — | US | disclosed |
| US-20070142377-A1 | Pyridyl Alkene and Pyridyl Alkine-Acid Amides as Cytostatics and Immunosuppressives | BIEDERMANN ELFI | 2007-06-21 | — | — | US | disclosed |
| US-20040009967-A1 | Pyridyl alkene- and pyridyl alkine- acid amides as cytostatics and immuno-suppressives | KLINGE PHARMA GMBH | 2004-01-15 | — | — | US | disclosed |
| EP-0923570-B1 | PYRIDYL ALKENE- AND PYRIDYL ALKINE- ACID AMIDES AS CYTOSTATICS AND IMMUNOSUPPRESSIVES | FUJISAWA DEUTSCHLAND GMBH (DE) | 2002-09-25 | — | — | EP | disclosed |
| US-5747206-A | Electrophotographic photoreceptor | FUJI XEROX CO., LTD. (JP) | 1998-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160085164-A1 | ELECTRON TRANSPORT MATERIAL, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS | GRK1, NR2E3, ATXN2L | MAPT 4324/4885ALDH1A1 1389/4885LMNA 2714/4885 |
| US-20070219197-A1 | Pyridyl alkene and pyridyl alkine- acid amides as cytostatics and immuno-suppressives | NFATC1, PDCD1, ACIN1 | MAPT 4047/4885ALDH1A1 690/4885LMNA 4358/4885 |
| US-20040009967-A1 | Pyridyl alkene- and pyridyl alkine- acid amides as cytostatics and immuno-suppressives | IDO1, ALK, ARG1 | MAPT 4119/4885ALDH1A1 173/4885LMNA 4478/4885 |
| US-20070142377-A1 | Pyridyl Alkene and Pyridyl Alkine-Acid Amides as Cytostatics and Immunosuppressives | ALK, TYMP, PDCD1 | MAPT 3831/4885ALDH1A1 266/4885LMNA 4007/4885 |
| US-20100130503-A1 | NEW FLUORENE DERIVATIVES, COMPOSITIONS CONTAINING THE SAME AND USE THEREOF AS INHIBITORS OF THE PROTEIN CHAPERONE HSP 90 | HSP90AB2P, HSPA2, HSP90AB1 | MAPT 1323/4885ALDH1A1 2540/4885LMNA 2105/4885 |
| US-20080153837-A1 | Novel Fluorene Derivatives, Composition Containing Said Derivatives and the Use Thereof | HSP90B1, HSP90AB1, HSP90AA1 | MAPT 844/4885ALDH1A1 3050/4885LMNA 3461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.