Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30553833 | 1.00 | HPGD (0.48) | HPGDMEN1ALDH1A1KMT2ATP53 | |
| SCHEMBL20796095 | 0.83 | MAPK1 (0.49) | HPGDMEN1ALDH1A1KMT2ATP53 | |
| SCHEMBL4778375 | 0.81 | HDAC8 (0.47) | TP53LMNAALOX15TSHRALPL | |
| SCHEMBL20796116 | 0.81 | ALDH1A1 (0.53) | HPGDMEN1ALDH1A1KMT2ATP53 | |
| SCHEMBL20772369 | 0.81 | CNR1 (0.47) | HPGDALDH1A1KMT2ATP53LMNA | |
| Hydrochloric Acid SCHEMBL30553806 | 0.80 | SMN1; SMN2 (0.47) | HPGDALDH1A1KMT2ATP53LMNA | |
| Hydrochloric Acid SCHEMBL22320782 | 0.80 | SMN1; SMN2 (0.47) | HPGDALDH1A1KMT2ATP53LMNA | |
| SCHEMBL20772525 | 0.77 | L3MBTL1 (0.58) | HPGDMEN1ALDH1A1KMT2ATP53 | |
| SCHEMBL20796246 | 0.76 | ALDH1A1 (0.59) | MEN1ALDH1A1KMT2ALMNAALPL | |
| SCHEMBL20772392 | 0.75 | ME2 (0.48) | LMNATSHRTDP1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3676260-B1 | THIOPHENE COMPOUNDS, PROCESS FOR SYNTHESIS AND USE THEREOF FOR THE TREATMENT OF AUTOIMMUNE DISORDERS | AHAMMUNE BIOSCIENCES PRIVATE LTD (IN) | 2024-10-30 | — | — | EP | claimed |
| US-11739082-B2 | Thiophene compounds, process for synthesis and use thereof | AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) | 2023-08-29 | — | — | US | claimed |
| US-20200255417-A1 | NOVEL THIOPHENE COMPOUNDS, PROCESS FOR SYNTHESIS AND USE THEREOF | AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) | 2020-08-13 | — | — | US | claimed |
| EP-3676260-A1 | NOVEL THIOPHENE COMPOUNDS, PROCESS FOR SYNTHESIS AND USE THEREOF | Ahammune Biosciences Private Limited (IN) | 2020-07-08 | — | — | EP | claimed |
| WO-2019043642-A1 | NOVEL THIOPHENE COMPOUNDS, PROCESS FOR SYNTHESIS AND USE THEREOF | AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) | 2019-03-07 | — | — | WO | claimed |
| EP-3676260-B1 | THIOPHENE COMPOUNDS, PROCESS FOR SYNTHESIS AND USE THEREOF FOR THE TREATMENT OF AUTOIMMUNE DISORDERS | AHAMMUNE BIOSCIENCES PRIVATE LTD (IN) | 2024-10-30 | — | — | EP | disclosed |
| US-11739082-B2 | Thiophene compounds, process for synthesis and use thereof | AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) | 2023-08-29 | — | — | US | disclosed |
| US-11739082-B2 | Thiophene compounds, process for synthesis and use thereof | AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) | 2023-08-29 | — | — | US | disclosed |
| US-11739082-B2 | Thiophene compounds, process for synthesis and use thereof | AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) | 2023-08-29 | — | — | US | disclosed |
| US-20200255417-A1 | NOVEL THIOPHENE COMPOUNDS, PROCESS FOR SYNTHESIS AND USE THEREOF | AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) | 2020-08-13 | — | — | US | disclosed |
| US-20200255417-A1 | NOVEL THIOPHENE COMPOUNDS, PROCESS FOR SYNTHESIS AND USE THEREOF | AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) | 2020-08-13 | — | — | US | disclosed |
| EP-3676260-A1 | NOVEL THIOPHENE COMPOUNDS, PROCESS FOR SYNTHESIS AND USE THEREOF | Ahammune Biosciences Private Limited (IN) | 2020-07-08 | — | — | EP | disclosed |
| WO-2019043642-A1 | NOVEL THIOPHENE COMPOUNDS, PROCESS FOR SYNTHESIS AND USE THEREOF | AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) | 2019-03-07 | — | — | WO | disclosed |
| WO-2019043642-A1 | NOVEL THIOPHENE COMPOUNDS, PROCESS FOR SYNTHESIS AND USE THEREOF | AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) | 2019-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11739082-B2 | Thiophene compounds, process for synthesis and use thereof | TPMT, TST, SSB | HPGD 2622/4885MEN1 1522/4885ALDH1A1 1352/4885 |
| US-20200255417-A1 | NOVEL THIOPHENE COMPOUNDS, PROCESS FOR SYNTHESIS AND USE THEREOF | TPMT, TST, UACA | HPGD 2777/4885MEN1 920/4885ALDH1A1 1873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.