Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | TYMS | P04818 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | VDR | P11473 | 1/20 | 0.49 |
| ▸ | SRC | P12931 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20772498 | 0.88 | GABRA2 (0.47) | POLBALDH1A1MAPTHTTKMT2A | |
| SCHEMBL20796116 | 0.88 | ALDH1A1 (0.53) | KDM1AMAOAMAOBTP53ALDH1A1 | |
| SCHEMBL20796243 | 0.87 | SMN1; SMN2 (0.50) | POLBKDM1AMAOAMAOBALDH1A1 | |
| SCHEMBL20772392 | 0.87 | ME2 (0.48) | MAPK1EGFRTYMSLTA4HVDR | |
| SCHEMBL20772497 | 0.86 | ALDH1A1 (0.48) | MAPK1EGFRTYMSLTA4HVDR | |
| SCHEMBL20772396 | 0.86 | FKBP1A (0.51) | MAPK1EGFRTYMSLTA4HVDR | |
| SCHEMBL20772402 | 0.83 | HPGD (0.48) | MAPK1POLBTP53ALDH1A1MAPT | |
| SCHEMBL30553833 | 0.83 | HPGD (0.48) | MAPK1POLBTP53ALDH1A1MAPT | |
| SCHEMBL20772483 | 0.82 | HSD11B1 (0.40) | MAPK1ALDH1A1MAPTLMNAHTT | |
| SCHEMBL20772371 | 0.81 | KDM1A (0.48) | POLBKDM1AMAOAMAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3676260-B1 | THIOPHENE COMPOUNDS, PROCESS FOR SYNTHESIS AND USE THEREOF FOR THE TREATMENT OF AUTOIMMUNE DISORDERS | AHAMMUNE BIOSCIENCES PRIVATE LTD (IN) | 2024-10-30 | — | — | EP | claimed |
| US-11739082-B2 | Thiophene compounds, process for synthesis and use thereof | AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) | 2023-08-29 | — | — | US | claimed |
| US-20200255417-A1 | NOVEL THIOPHENE COMPOUNDS, PROCESS FOR SYNTHESIS AND USE THEREOF | AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) | 2020-08-13 | — | — | US | claimed |
| EP-3676260-B1 | THIOPHENE COMPOUNDS, PROCESS FOR SYNTHESIS AND USE THEREOF FOR THE TREATMENT OF AUTOIMMUNE DISORDERS | AHAMMUNE BIOSCIENCES PRIVATE LTD (IN) | 2024-10-30 | — | — | EP | disclosed |
| US-11739082-B2 | Thiophene compounds, process for synthesis and use thereof | AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) | 2023-08-29 | — | — | US | disclosed |
| US-11739082-B2 | Thiophene compounds, process for synthesis and use thereof | AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) | 2023-08-29 | — | — | US | disclosed |
| US-11739082-B2 | Thiophene compounds, process for synthesis and use thereof | AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) | 2023-08-29 | — | — | US | disclosed |
| US-20200255417-A1 | NOVEL THIOPHENE COMPOUNDS, PROCESS FOR SYNTHESIS AND USE THEREOF | AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) | 2020-08-13 | — | — | US | disclosed |
| US-20200255417-A1 | NOVEL THIOPHENE COMPOUNDS, PROCESS FOR SYNTHESIS AND USE THEREOF | AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) | 2020-08-13 | — | — | US | disclosed |
| WO-2019043642-A1 | NOVEL THIOPHENE COMPOUNDS, PROCESS FOR SYNTHESIS AND USE THEREOF | AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) | 2019-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11739082-B2 | Thiophene compounds, process for synthesis and use thereof | TPMT, TST, SSB | MAPK1 2166/4885EGFR 4645/4885TYMS 18/4885 |
| US-20200255417-A1 | NOVEL THIOPHENE COMPOUNDS, PROCESS FOR SYNTHESIS AND USE THEREOF | TPMT, TST, UACA | MAPK1 2667/4885EGFR 4630/4885TYMS 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.