Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 8/20 | 0.39 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.35 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20804162 | 0.76 | HDAC1 (0.33) | RIPK1MEP1B | |
| SCHEMBL20804235 | 0.71 | HSP90AA1 (0.43) | POLB | |
| SCHEMBL22018330 | 0.69 | NPC1 (0.54) | RIPK1MEN1KMT2A | |
| SCHEMBL20804153 | 0.67 | HSP90AA1 (0.48) | MEN1KMT2APOLBTDP1 | |
| SCHEMBL4621767 | 0.67 | MAPK1 (0.36) | RIPK1 | |
| SCHEMBL19577474 | 0.65 | SMN1; SMN2 (0.56) | MEN1KMT2ATDP1 | |
| SCHEMBL11967063 | 0.65 | RIPK1 (0.38) | RIPK1 | |
| SCHEMBL18216781 | 0.64 | HTR2A (0.33) | RIPK1HTR2A | |
| SCHEMBL586106 | 0.63 | CTSL (0.33) | — | |
| SCHEMBL25583240 | 0.62 | CASP1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3089962-B1 | RADIOIODINATED COMPOUNDS | NUTECH VENTURES (US) | 2019-03-13 | — | — | EP | disclosed |