SCHEMBL20809031

SCHEMBL20809031

Cc1cccc(-c2ccc3cc(CC4CCCC4)ccc3n2)c1

nearest known ligand 0.50

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 12/20 0.42
HRH3 Q9Y5N1 12/20 0.42
HTR6 P50406 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20809422 0.91 HTR6 (0.41) HTR6
SCHEMBL20809030 0.89 HTR6 (0.43) KCNH2HRH3HTR6
SCHEMBL20809032 0.86 KCNH2 (0.44) KCNH2HRH3HTR6
SCHEMBL20809129 0.80 ACP1 (0.42) HTR6
SCHEMBL20809423 0.80 HTR6 (0.43) KCNH2HRH3HTR6
SCHEMBL20809307 0.79 BACE1 (0.51) HRH3
SCHEMBL20809026 0.78 BACE1 (0.53) HRH3
SCHEMBL20809123 0.77 ITGB1 (0.39) KCNH2HRH3
SCHEMBL20809065 0.77 GRM2 (0.43) KCNH2HRH3
SCHEMBL3296780 0.77 CYP1A2 (0.53)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10957869-B2 Organic luminescent materials containing cycloalkyl ancillary ligands Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-03-23 US disclosed
US-20190103574-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-04-04 US disclosed
US-20190077818-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190103574-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS ACAT1, ACACA, ACAT2 KCNH2 712/4885HRH3 3599/4885HTR6 768/4885
US-10957869-B2 Organic luminescent materials containing cycloalkyl ancillary ligands ACAT1, ACACA, ACAT2 KCNH2 712/4885HRH3 3599/4885HTR6 768/4885
US-20190077818-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS FOXO1, NAA15, FOXK1 KCNH2 573/4885HRH3 3421/4885HTR6 552/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.