SCHEMBL20809307

SCHEMBL20809307

Cc1cccc(-c2ccc3cc(C4CCCC4)ccc3n2)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.51
CASP3 P42574 1/20 0.45
SENP7 Q9BQF6 1/20 0.45
SENP6 Q9GZR1 1/20 0.45
KDM1A O60341 1/20 0.43
HRH3 Q9Y5N1 1/20 0.43
CTSS P25774 2/20 0.40
CTSK P43235 2/20 0.40
HTR2C P28335 2/20 0.39
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
XBP1 P17861 1/20 0.38
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
PSMB5 P28074 1/20 0.38
PFKFB3 Q16875 1/20 0.38
SOS1 Q07889 1/20 0.38
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
DHODH Q02127 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20809026 0.99 BACE1 (0.53) BACE1CASP3SENP7SENP6KDM1A
SCHEMBL20809303 0.91 CASP3 (0.46) BACE1CASP3SENP7SENP6KDM1A
SCHEMBL20809060 0.90 CASP3 (0.48) BACE1CASP3SENP7SENP6KDM1A
SCHEMBL20809309 0.88 BACE1 (0.55) BACE1CASP3SENP7SENP6HRH3
SCHEMBL20809057 0.86 BACE1 (0.57) BACE1CASP3SENP7SENP6HRH3
SCHEMBL20809362 0.85 BACE1 (0.57) BACE1HRH3MAPTHTTSMN1; SMN2
SCHEMBL20809028 0.83 BACE1 (0.60) BACE1CASP3SENP7SENP6HRH3
SCHEMBL3296780 0.80 CYP1A2 (0.53) BACE1SMN1; SMN2PSMB5NPC1RAB9A
SCHEMBL20809031 0.79 KCNH2 (0.42) HRH3
SCHEMBL20809079 0.78 BACE1 (0.42) BACE1CASP3SENP7SENP6HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10957869-B2 Organic luminescent materials containing cycloalkyl ancillary ligands Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-03-23 US disclosed
US-20190103574-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-04-04 US disclosed
US-20190077818-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190103574-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS ACAT1, ACACA, ACAT2 BACE1 3381/4885CASP3 3135/4885SENP7 4161/4885
US-10957869-B2 Organic luminescent materials containing cycloalkyl ancillary ligands ACAT1, ACACA, ACAT2 BACE1 3381/4885CASP3 3135/4885SENP7 4161/4885
US-20190077818-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS FOXO1, NAA15, FOXK1 BACE1 3964/4885CASP3 3201/4885SENP7 4462/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.