SCHEMBL20809296

SCHEMBL20809296

c1ccc(-c2cc(C3CCCC3)c3ccccc3n2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 2/20 0.54
ACHE P22303 1/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
TDP1 Q9NUW8 1/20 0.51
KDM4E B2RXH2 2/20 0.50
HPGD P15428 2/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
ALDH1A1 P00352 1/20 0.49
POLB P06746 1/20 0.49
LMNA P02545 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
PDE10A Q9Y233 1/20 0.47
ADORA3 P0DMS8 2/20 0.46
ADORA2B P29275 2/20 0.46
ADORA1 P30542 2/20 0.46
ADORA2A P29274 1/20 0.45
ACACA Q13085 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20809082 0.98 DHODH (0.56) DHODHACHEL3MBTL1TDP1KDM4E
SCHEMBL20809292 0.87 ACP1 (0.47) DHODHL3MBTL1TDP1KDM4EHPGD
SCHEMBL20809293 0.87 DHODH (0.46) DHODHACHEL3MBTL1TDP1KDM4E
SCHEMBL20809083 0.86 ACP1 (0.49) DHODHL3MBTL1TDP1KDM4EHPGD
SCHEMBL20809084 0.86 DHODH (0.48) DHODHL3MBTL1TDP1KDM4EHPGD
SCHEMBL26061430 0.84 KDM4E (0.46) DHODHACHEL3MBTL1TDP1KDM4E
SCHEMBL20809365 0.83 L3MBTL1 (0.47) DHODHACHEL3MBTL1TDP1KDM4E
SCHEMBL28708591 0.82 CYP1A2 (0.53) L3MBTL1TDP1KDM4EHPGDMEN1
SCHEMBL28603583 0.82 POLB (0.53) DHODHL3MBTL1TDP1KDM4EHPGD
SCHEMBL20809080 0.81 L3MBTL1 (0.49) DHODHACHEL3MBTL1TDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10957869-B2 Organic luminescent materials containing cycloalkyl ancillary ligands Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-03-23 US disclosed
US-20190103574-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-04-04 US disclosed
US-20190077818-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190103574-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS ACAT1, ACACA, ACAT2 DHODH 3548/4885ACHE 37/4885L3MBTL1 2059/4885
US-10957869-B2 Organic luminescent materials containing cycloalkyl ancillary ligands ACAT1, ACACA, ACAT2 DHODH 3548/4885ACHE 37/4885L3MBTL1 2059/4885
US-20190077818-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS FOXO1, NAA15, FOXK1 DHODH 2970/4885ACHE 6/4885L3MBTL1 1986/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.