SCHEMBL20809293

SCHEMBL20809293

Cc1cc(C)cc(-c2cc(C3CCCC3)c3ccccc3n2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 1/20 0.46
PSMB5 P28074 1/20 0.45
L3MBTL1 Q9Y468 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
HPGD P15428 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
ALDH1A1 P00352 1/20 0.42
POLB P06746 1/20 0.42
KDM4E B2RXH2 2/20 0.42
CAMKK1 Q8N5S9 2/20 0.41
CAMKK2 Q96RR4 2/20 0.41
ADORA3 P0DMS8 1/20 0.40
ADORA2A P29274 1/20 0.40
ADORA1 P30542 1/20 0.40
LMNA P02545 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
PDE5A O76074 1/20 0.40
RAB9A P51151 1/20 0.40
NCF1 P14598 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20809084 0.99 DHODH (0.48) DHODHPSMB5L3MBTL1TDP1HPGD
SCHEMBL20809292 0.89 ACP1 (0.47) DHODHL3MBTL1TDP1HPGDMEN1
SCHEMBL24795691 0.89 DHODH (0.41) DHODHPSMB5L3MBTL1TDP1HPGD
SCHEMBL20809083 0.88 ACP1 (0.49) DHODHPSMB5L3MBTL1TDP1HPGD
SCHEMBL24795840 0.88 DHODH (0.42) DHODHPSMB5L3MBTL1TDP1HPGD
SCHEMBL20809296 0.87 DHODH (0.54) DHODHL3MBTL1TDP1HPGDMEN1
SCHEMBL26719658 0.86 KDM4E (0.39) DHODHPSMB5L3MBTL1TDP1HPGD
SCHEMBL20809082 0.85 DHODH (0.56) DHODHL3MBTL1TDP1HPGDMEN1
SCHEMBL24796168 0.85 PSMB5 (0.44) DHODHPSMB5MEN1KMT2AALDH1A1
SCHEMBL15377440 0.85 PSMB5 (0.44) DHODHPSMB5L3MBTL1TDP1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220402877-A1 ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-12-22 US disclosed
US-10957869-B2 Organic luminescent materials containing cycloalkyl ancillary ligands Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-03-23 US disclosed
US-20190103574-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-04-04 US disclosed
US-20190077818-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190103574-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS ACAT1, ACACA, ACAT2 DHODH 3548/4885PSMB5 4813/4885L3MBTL1 2059/4885
US-10957869-B2 Organic luminescent materials containing cycloalkyl ancillary ligands ACAT1, ACACA, ACAT2 DHODH 3548/4885PSMB5 4813/4885L3MBTL1 2059/4885
US-20220402877-A1 ELECTROLUMINESCENT DEVICE MCOLN2, MCOLN1, LDHB DHODH 1700/4885PSMB5 3344/4885L3MBTL1 47/4885
US-20190077818-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS FOXO1, NAA15, FOXK1 DHODH 2970/4885PSMB5 4831/4885L3MBTL1 1986/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.