Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18041442 | 0.95 | RAB9A (0.52) | RAB9AALDH1A1HPGDSMN1; SMN2ACHE | |
| SCHEMBL3508948 | 0.80 | SMN1; SMN2 (0.62) | ALDH1A1SMN1; SMN2LMNATSHR | |
| SCHEMBL20819322 | 0.80 | SMN1; SMN2 (0.46) | SMN1; SMN2CYP2D6CYP2C9CYP2C19MAOB | |
| SCHEMBL29778208 | 0.80 | ALOX5 (0.53) | RAB9AALDH1A1HPGDSMN1; SMN2ACHE | |
| SCHEMBL18059295 | 0.80 | ALOX5 (0.53) | RAB9AALDH1A1HPGDSMN1; SMN2ACHE | |
| SCHEMBL926393 | 0.79 | TSHR (0.51) | RAB9AALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL17162119 | 0.79 | SMN1; SMN2 (0.60) | RAB9AALDH1A1SMN1; SMN2LMNATSHR | |
| SCHEMBL6253038 | 0.78 | HTR1A (0.51) | RAB9AALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL10364018 | 0.78 | TGM2 (0.48) | RAB9AALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL18051125 | 0.78 | MEN1 (0.53) | RAB9AALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019053617-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-03-21 | — | — | WO | disclosed |