Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.60 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.60 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.59 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.49 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29444458 | 1.00 | MTNR1A (0.60) | MTNR1AMTNR1BNR4A2GPR84KDM4E | |
| SCHEMBL498040 | 0.89 | CHRNB2 (0.56) | MTNR1AMTNR1BNR4A2GPR84KDM4E | |
| SCHEMBL29506986 | 0.89 | CHRNB2 (0.56) | MTNR1AMTNR1BNR4A2GPR84KDM4E | |
| SCHEMBL3030323 | 0.86 | MTNR1A (0.64) | MTNR1AMTNR1BNR4A2GPR84KDM4E | |
| SCHEMBL30419995 | 0.86 | PKM (0.67) | MTNR1AMTNR1BNR4A2GPR84KDM4E | |
| SCHEMBL3703101 | 0.86 | PKM (0.67) | MTNR1AMTNR1BNR4A2GPR84KDM4E | |
| SCHEMBL21255987 | 0.84 | MTNR1A (0.59) | MTNR1AMTNR1BNR4A2KDM4EHTR2A | |
| SCHEMBL853729 | 0.84 | NPSR1 (0.68) | KDM4EHTR2AIDO1MEN1KMT2A | |
| SCHEMBL20769666 | 0.83 | MTNR1A (0.60) | MTNR1AMTNR1BNR4A2GPR84KDM4E | |
| SCHEMBL2686551 | 0.83 | KDM4E (0.77) | MTNR1AMTNR1BNR4A2GPR84KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12553055-B2 | Auxin-inducible degron system kit and use thereof | INTER-UNIVERSITY RESEARCH INSTITUTE CORPORATION RESEARCH ORGANIZATION OF INFORMATION AND SYSTEMS (JP) | 2026-02-17 | — | — | US | disclosed |
| US-12522836-B2 | Nonhuman animal and use for same | Inter-University Reseach Institute Corporation Research Organization of Informaton and Systems (JP) | 2026-01-13 | — | — | US | disclosed |
| US-20250340551-A1 | SMALL MOLECULE MODULATORS OF STAT6 | GILEAD SCIENCES INC (US) | 2025-11-06 | — | — | US | disclosed |
| US-20250325677-A1 | STAT6 DEGRADERS | GILEAD SCIENCES INC (US) | 2025-10-23 | — | — | US | disclosed |
| CN-114057759-B | Fused tetracyclic derivative, preparation method thereof and application thereof in medicines | 江苏恒瑞医药股份有限公司 | 2023-05-16 | — | — | CN | disclosed |
| US-20220380782-A1 | AUXIN-INDUCIBLE DEGRON SYSTEM KIT AND USE THEREOF | KAKE EDUCATIONAL INSTITUTION (JP) | 2022-12-01 | — | — | US | disclosed |
| US-20220378024-A1 | NONHUMAN ANIMAL AND USE FOR SAME | KAKE EDUCATIONAL INSTITUTION (JP) | 2022-12-01 | — | — | US | disclosed |
| EP-4026828-A1 | AUXIN-INDUCIBLE DEGRON SYSTEM KIT AND USE THEREOF | Inter-University Research Institute Corporation Research Organization of Information and Systems (JP) | 2022-07-13 | — | — | EP | disclosed |
| EP-4026828-A1 | AUXIN-INDUCIBLE DEGRON SYSTEM KIT AND USE THEREOF | Inter-University Research Institute Corporation Research Organization of Information and Systems (JP) | 2022-07-13 | — | — | EP | disclosed |
| EP-4001414-A1 | NONHUMAN ANIMAL AND USE FOR SAME | Inter-University Research Institute Corporation Research Organization of Information and Systems (JP) | 2022-05-25 | — | — | EP | disclosed |
| US-7601751-B2 | Indole acetic acid acyl guanidines as β-secretase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-10-13 | — | — | US | disclosed |
| EP-2029547-A1 | FXR AGONISTS | ELI LILLY AND COMPANY (US) | 2009-03-04 | — | — | EP | disclosed |
| US-20080306125-A1 | Compounds and Methods for Modulating Fx-Receptors | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR COLLATERAL AGENT | 2008-12-11 | — | — | US | disclosed |
| EP-1984360-A2 | COMPOUNDS AND METHODS FOR MODULATING FX-RECEPTORS | Eli Lilly & Company (US) | 2008-10-29 | — | — | EP | disclosed |
| WO-2007140183-A1 | FXR AGONISTS | ELI LILLY AND COMPANY (US) | 2007-12-06 | — | — | WO | disclosed |
| WO-2007092751-A2 | COMPOUNDS AND METHODS FOR MODULATING FX-RECEPTORS | ELI LILLY AND COMPANY (US) | 2007-08-16 | — | — | WO | disclosed |
| WO-2007075931-A2 | REACTIVE HETEROCYCLIC DERIVATIVES AND METHODS FOR THEIR SYNTHESIS AND USE | BIOSITE INCORPORATED (US) | 2007-07-05 | — | — | WO | disclosed |
| WO-2007075931-A2 | REACTIVE HETEROCYCLIC DERIVATIVES AND METHODS FOR THEIR SYNTHESIS AND USE | BIOSITE INCORPORATED (US) | 2007-07-05 | — | — | WO | disclosed |
| US-20070049589-A1 | Indole acetic acid acyl guanidines as beta-secretase inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2007-03-01 | — | — | US | disclosed |
| EP-0252404-A2 | 5-Hydroxy-3-indoleacetic acid fluorescence polarization immunoassay | ABBOTT LABORATORIES (US) | 1988-01-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070049589-A1 | Indole acetic acid acyl guanidines as beta-secretase inhibitors | BACE1, APP, BACE2 | MTNR1A 1114/4885MTNR1B 949/4885NR4A2 2491/4885 |
| US-20220378024-A1 | NONHUMAN ANIMAL AND USE FOR SAME | MDM2, CUL1, STUB1 | MTNR1A 338/4885MTNR1B 826/4885NR4A2 2811/4885 |
| US-20250325677-A1 | STAT6 DEGRADERS | STAT6, STAT5B, STAT1 | MTNR1A 425/4885MTNR1B 546/4885NR4A2 222/4885 |
| US-20080306125-A1 | Compounds and Methods for Modulating Fx-Receptors | F2R, TBXA2R, PTAFR | MTNR1A 134/4885MTNR1B 129/4885NR4A2 1079/4885 |
| US-20250340551-A1 | SMALL MOLECULE MODULATORS OF STAT6 | STAT6, STAT1, STAT5B | MTNR1A 849/4885MTNR1B 912/4885NR4A2 372/4885 |
| US-12553055-B2 | Auxin-inducible degron system kit and use thereof | GET3, STUB1, TOE1 | MTNR1A 1092/4885MTNR1B 1867/4885NR4A2 1953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.