Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.45 |
| ▸ | EPAS1 | Q99814 | 8/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.42 |
| ▸ | GRK2 | P25098 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22227863 | 0.82 | PPARG (0.48) | FFAR1DGAT1ROCK2GRK2 | |
| SCHEMBL20828478 | 0.81 | FFAR1 (0.45) | RAB9AFFAR1DGAT1ROCK2GRK2 | |
| SCHEMBL20828423 | 0.80 | DGAT1 (0.44) | RAB9ADGAT1ROCK2GRK2 | |
| SCHEMBL20828481 | 0.80 | FFAR1 (0.45) | RAB9AFFAR1DGAT1ROCK2GRK2 | |
| SCHEMBL20828416 | 0.79 | DGAT1 (0.45) | RAB9ADGAT1ROCK2GRK2 | |
| SCHEMBL20832631 | 0.78 | MAOA (0.44) | FFAR1DGAT1ROCK2GRK2 | |
| SCHEMBL20828479 | 0.78 | F10 (0.48) | KDM4E | |
| SCHEMBL20828419 | 0.78 | L3MBTL1 (0.42) | RAB9AFFAR1ROCK2GRK2 | |
| SCHEMBL20828529 | 0.77 | HIF1A (0.46) | HIF1AEPAS1RAB9APDGFRAS1PR1 | |
| SCHEMBL20828341 | 0.75 | DGAT1 (0.48) | RAB9ADGAT1ROCK2KDM4EOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019054430-A1 | AMIDE COMPOUND HAVING AROMATIC HETEROCYCLE | 第一三共株式会社 | 2019-03-21 | — | — | WO | disclosed |
| WO-2019054430-A1 | AMIDE COMPOUND HAVING AROMATIC HETEROCYCLE | 第一三共株式会社 | 2019-03-21 | — | — | WO | disclosed |