Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | DGAT1 | O75907 | 6/20 | 0.41 |
| ▸ | BRAF | P15056 | 2/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
| ▸ | GRK2 | P25098 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20828478 | 0.91 | FFAR1 (0.45) | FFAR1DGAT1RAF1MAPK14ROCK2 | |
| SCHEMBL22227863 | 0.83 | PPARG (0.48) | FFAR1DGAT1ROCK2GRK2CETP | |
| SCHEMBL20828451 | 0.82 | BRAF (0.44) | BRAFRAF1MAPK14ROCK2GRK2 | |
| SCHEMBL20828420 | 0.81 | DGAT1 (0.47) | DGAT1ROCK2RAB9A | |
| SCHEMBL20828341 | 0.81 | DGAT1 (0.48) | DGAT1ROCK2RAB9A | |
| SCHEMBL20820816 | 0.80 | HIF1A (0.45) | FFAR1DGAT1ROCK2GRK2RAB9A | |
| SCHEMBL20828340 | 0.79 | BRAF (0.46) | DGAT1BRAFRAF1MAPK14ROCK2 | |
| SCHEMBL20832631 | 0.79 | MAOA (0.44) | FFAR1DGAT1ROCK2GRK2CETP | |
| SCHEMBL20828417 | 0.78 | ROCK2 (0.46) | DGAT1MAPK14ROCK2RAB9A | |
| SCHEMBL20828419 | 0.77 | L3MBTL1 (0.42) | FFAR1ROCK2GRK2CETPRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019054430-A1 | AMIDE COMPOUND HAVING AROMATIC HETEROCYCLE | 第一三共株式会社 | 2019-03-21 | — | — | WO | disclosed |