Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 9/20 | 0.46 |
| ▸ | EPAS1 | Q99814 | 9/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20828389 | 0.84 | FFAR1 (0.46) | HIF1AEPAS1FFAR1PTPN1RAB9A | |
| SCHEMBL20828525 | 0.83 | RAB9A (0.45) | FFAR1PTPN1RAB9AGAAMAPT | |
| SCHEMBL20828380 | 0.82 | CSF1R (0.47) | FFAR1RAB9AGAAMAPT | |
| SCHEMBL20820816 | 0.77 | HIF1A (0.45) | HIF1AEPAS1S1PR5PDGFRAS1PR1 | |
| SCHEMBL20828384 | 0.76 | RXFP1 (0.47) | FFAR1KDM4E | |
| SCHEMBL20828516 | 0.75 | RAB9A (0.50) | HIF1AEPAS1FFAR1PTPN1RAB9A | |
| SCHEMBL20828477 | 0.74 | RXFP1 (0.45) | FFAR1RAB9AKDM4EMAPT | |
| SCHEMBL22237402 | 0.71 | LMNA (0.52) | KDM4E | |
| SCHEMBL31395035 | 0.68 | S1PR5 (0.82) | S1PR5PDGFRAS1PR1GAAKDM4E | |
| SCHEMBL18083684 | 0.66 | SLC2A1 (0.69) | HIF1AEPAS1RAB9AGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019054430-A1 | AMIDE COMPOUND HAVING AROMATIC HETEROCYCLE | 第一三共株式会社 | 2019-03-21 | — | — | WO | disclosed |