Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.42 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.42 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.42 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.42 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20828389 | 0.90 | FFAR1 (0.46) | RAB9AGAAMAPTMAPK1L3MBTL1 | |
| SCHEMBL20828525 | 0.76 | RAB9A (0.45) | RAB9AGAAMAPTMAPK1L3MBTL1 | |
| SCHEMBL20828380 | 0.76 | CSF1R (0.47) | RAB9AGAAMAPTMAPK1L3MBTL1 | |
| SCHEMBL20828529 | 0.75 | HIF1A (0.46) | RAB9AGAAMAPTFFAR1HIF1A | |
| SCHEMBL20828451 | 0.71 | BRAF (0.44) | RAB9ARAF1BRAFMAPK14ROCK2 | |
| SCHEMBL20828384 | 0.70 | RXFP1 (0.47) | FFAR1KDM4EMEN1KMT2A | |
| SCHEMBL20828477 | 0.69 | RXFP1 (0.45) | RAB9AMAPTFFAR1KDM4E | |
| SCHEMBL20828481 | 0.68 | FFAR1 (0.45) | RAB9AFFAR1RAF1BRAFMAPK14 | |
| SCHEMBL5934735 | 0.66 | P4HTM (0.56) | RAB9AMAPTMAPK1L3MBTL1KDM4E | |
| SCHEMBL14083005 | 0.66 | MAPT (0.53) | RAB9AMAPTMAPK14KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019054430-A1 | AMIDE COMPOUND HAVING AROMATIC HETEROCYCLE | 第一三共株式会社 | 2019-03-21 | — | — | WO | disclosed |