Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 3/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 3/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | WNT1 | P04628 | 1/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.42 |
| ▸ | CLK3 | P49761 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MTTP | P55157 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
| ▸ | GRK2 | P25098 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | LSS | P48449 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20828481 | 0.82 | FFAR1 (0.45) | BRAFRAF1MAPK14RAB9AROCK2 | |
| SCHEMBL20828440 | 0.82 | MAOA (0.42) | GSK3BDYRK1AROCK2GRK2PPARG | |
| SCHEMBL20828420 | 0.81 | DGAT1 (0.47) | DYRK1ARAB9AROCK2SLC2A1 | |
| SCHEMBL20828341 | 0.79 | DGAT1 (0.48) | RAB9AROCK2SLC2A1 | |
| SCHEMBL20828340 | 0.78 | BRAF (0.46) | BRAFRAF1MAPK14ROCK2GRK2 | |
| SCHEMBL20820816 | 0.77 | HIF1A (0.45) | RAB9AROCK2GRK2 | |
| SCHEMBL20828417 | 0.76 | ROCK2 (0.46) | MAPK14RAB9AROCK2SLC2A1 | |
| SCHEMBL22227863 | 0.76 | PPARG (0.48) | ROCK2GRK2PPARG | |
| SCHEMBL20828519 | 0.76 | SLC6A5 (0.51) | RAB9APPARG | |
| SCHEMBL20828450 | 0.75 | L3MBTL1 (0.47) | RAB9APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019054430-A1 | AMIDE COMPOUND HAVING AROMATIC HETEROCYCLE | 第一三共株式会社 | 2019-03-21 | — | — | WO | disclosed |