Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | KAT2B | Q92831 | 10/20 | 0.46 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | BPTF | Q12830 | 1/20 | 0.41 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2550526 | 0.87 | ALDH1A1 (0.58) | ALDH1A1PKMNPC1KAT2BBRD9 | |
| SCHEMBL2549761 | 0.85 | RAB9A (0.59) | ALDH1A1PKMNPC1KAT2BBRD9 | |
| SCHEMBL2547161 | 0.85 | ALDH1A1 (0.60) | ALDH1A1PKMNPC1KAT2BBRD9 | |
| SCHEMBL9124077 | 0.83 | PKM (0.54) | ALDH1A1PKMNPC1KAT2BBRD9 | |
| SCHEMBL16133060 | 0.80 | ALDH1A1 (0.55) | ALDH1A1PKMNPC1KAT2BBRD9 | |
| SCHEMBL23573211 | 0.78 | ALDH1A1 (0.50) | ALDH1A1PKMNPC1KAT2BBRD9 | |
| SCHEMBL20818806 | 0.70 | ALDH1A1 (0.40) | ALDH1A1PKMNPC1GAARAB9A | |
| SCHEMBL9125507 | 0.70 | ALDH1A1 (0.47) | ALDH1A1PKMNPC1DCTPP1 | |
| SCHEMBL9125502 | 0.70 | ALDH1A1 (0.47) | ALDH1A1PKMNPC1DCTPP1 | |
| SCHEMBL27264164 | 0.70 | BPTF (0.52) | ALDH1A1PKMNPC1KAT2BBPTF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019055966-A2 | PYRIDAZINONES AND METHODS OF USE THEREOF | GOLDFINCH BIO, INC. (US) | 2019-03-21 | — | — | WO | disclosed |