Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TSPO | P30536 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20835004 | 0.85 | FFAR1 (0.35) | FFAR1FFAR4ALDH1A1MAPTPOLB | |
| SCHEMBL20834702 | 0.84 | FFAR1 (0.35) | FFAR1FFAR4ALDH1A1MAPTPOLB | |
| SCHEMBL20835006 | 0.84 | FFAR1 (0.32) | FFAR1FFAR4ALDH1A1 | |
| SCHEMBL23309982 | 0.84 | FFAR1 (0.34) | FFAR1FFAR4ALDH1A1MAPTPOLB | |
| SCHEMBL26187789 | 0.83 | HSD17B1 (0.39) | FFAR1FFAR4ALDH1A1MAPTPOLB | |
| SCHEMBL23309986 | 0.82 | ALDH1A1 (0.31) | ALDH1A1MAPTPOLB | |
| SCHEMBL20834892 | 0.82 | FFAR1 (0.34) | FFAR1FFAR4ALDH1A1MAPTPOLB | |
| SCHEMBL22622787 | 0.81 | ACACB (0.39) | FFAR1FFAR4ALDH1A1MAPTPOLB | |
| SCHEMBL24940701 | 0.80 | FFAR1 (0.31) | FFAR1FFAR4 | |
| SCHEMBL20834898 | 0.80 | FFAR1 (0.36) | FFAR1FFAR4TSPODRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240072425-A1 | AROMATIC ISOTHIOCYANATES | MERCK PATENT GMBH (DE) | 2024-02-29 | — | — | US | disclosed |
| US-11739265-B2 | Aromatic isothiocyanates | MERCK PATENT GMBH (DE) | 2023-08-29 | — | — | US | disclosed |
| US-20230025385-A1 | FLUORINATED AROMATIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2023-01-26 | — | — | US | disclosed |
| US-11306251-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2022-04-19 | — | — | US | disclosed |
| US-11268026-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2022-03-08 | — | — | US | disclosed |
| EP-3681976-B1 | ISOTHIOCYANATO TOLANE DERIVATIVES | MERCK PATENT GMBH (DE) | 2021-05-26 | — | — | EP | disclosed |
| US-20210122977-A1 | ISOTHIOCYANATO TOLANE DERIVATIVES | MERCK PATENT GMBH (DE) | 2021-04-29 | — | — | US | disclosed |
| US-20200347301-A1 | Isothiocyanato-tolanes | MERCK PATENT GMBH (DE) | 2020-11-05 | — | — | US | disclosed |
| US-20190352564-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2019-11-21 | — | — | US | disclosed |
| US-20190292460-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2019-09-26 | — | — | US | disclosed |
| US-20190292458-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2019-09-26 | — | — | US | disclosed |
| WO-2019052972-A1 | ISOTHIOCYANATO TOLANE DERIVATIVES | MERCK PATENT GMBH (DE) | 2019-03-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240072425-A1 | AROMATIC ISOTHIOCYANATES | TRPA1, TRPC1, CRY1 | FFAR1 4239/4885FFAR4 4575/4885ALDH1A1 1864/4885 |
| US-20230025385-A1 | FLUORINATED AROMATIC COMPOUNDS | TRPA1, FOXM1, AFF1 | FFAR1 3189/4885FFAR4 3852/4885ALDH1A1 1136/4885 |
| US-11739265-B2 | Aromatic isothiocyanates | TRPA1, CRY1, FOXM1 | FFAR1 4387/4885FFAR4 4573/4885ALDH1A1 1554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.