Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 9/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 2/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | WNT1 | P04628 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20845987 | 0.86 | ABL1 (0.35) | ABL1PTGESTLR7DYRK1A | |
| SCHEMBL20839264 | 0.82 | CYP11B2 (0.36) | ABL1PTGESDYRK1A | |
| SCHEMBL20843729 | 0.80 | ABL1 (0.33) | ABL1PTGESTLR7DYRK1AADORA2A | |
| SCHEMBL24013175 | 0.74 | PTGES (0.33) | ABL1PTGESTLR7 | |
| SCHEMBL19406218 | 0.73 | KDR (0.42) | ABL1HCRTR1HCRTR2KDRPTGES | |
| SCHEMBL19406423 | 0.73 | SMN1; SMN2 (0.35) | ABL1HCRTR1HCRTR2PTGESTLR7 | |
| SCHEMBL20846004 | 0.72 | KDM4E (0.34) | ABL1 | |
| SCHEMBL19406487 | 0.71 | TLR7 (0.34) | ABL1HCRTR1HCRTR2PTGESTLR7 | |
| SCHEMBL20846007 | 0.69 | KDR (0.43) | HCRTR1HCRTR2KDRDYRK1ACYP3A4 | |
| SCHEMBL20845492 | 0.69 | ABL1 (0.38) | ABL1KDRDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11678665-B2 | Pyrazine-4-carbamate or -urea derivatives as herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2023-06-20 | — | — | US | disclosed |
| US-11678665-B2 | Pyrazine-4-carbamate or -urea derivatives as herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2023-06-20 | — | — | US | disclosed |
| EP-3684764-B1 | PYRAZINE-4-CARBAMATE DERIVATIVES AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2021-11-10 | — | — | EP | disclosed |
| US-20200267983-A1 | Pyrazine-4Carbamate or -Urea Derivatives As Herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-27 | — | — | US | disclosed |
| WO-2019057724-A1 | PYRAZINE-4CARBAMATE OR -UREA DERIVATIVES AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-03-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11678665-B2 | Pyrazine-4-carbamate or -urea derivatives as herbicides | DDT, PLPBP, CPS1 | ABL1 2259/4885HCRTR1 2739/4885HCRTR2 3417/4885 |
| US-20200267983-A1 | Pyrazine-4Carbamate or -Urea Derivatives As Herbicides | PLPBP, PDXK, HPD | ABL1 2740/4885HCRTR1 2735/4885HCRTR2 3309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.