Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.31 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20847477 | 0.84 | SLC6A2 (0.39) | ALDH1A1KDM4EHDAC6HDAC8 | |
| SCHEMBL20847664 | 0.82 | ESR1 (0.38) | ALDH1A1HDAC6CYP19A1HDAC8 | |
| SCHEMBL20847604 | 0.82 | SLC6A2 (0.38) | HDAC6CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL20847602 | 0.80 | AGER (0.38) | ALDH1A1LMNAHDAC6HDAC8 | |
| SCHEMBL20847642 | 0.79 | SLC6A4 (0.35) | ALDH1A1KDM4ELMNAHDAC6HDAC8 | |
| SCHEMBL20847669 | 0.79 | AGER (0.40) | ALDH1A1LMNAHDAC6CYP3A4CYP2D6 | |
| SCHEMBL20847622 | 0.78 | L3MBTL1 (0.40) | ALDH1A1 | |
| SCHEMBL20847740 | 0.78 | NSD2 (0.47) | CYP19A1 | |
| SCHEMBL20847575 | 0.78 | AGER (0.42) | ALDH1A1LMNACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL20847775 | 0.77 | KMT2A (0.44) | ALDH1A1HDAC6HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019056120-A1 | PENTAFLUOROPHENYL SULFONAMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | DALRIADA THERAPEUTICS INC. (CA) | 2019-03-28 | — | — | WO | disclosed |