Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 4/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20847650 | 0.84 | ALDH1A1 (0.35) | HDAC6HDAC8KDM4EALDH1A1 | |
| SCHEMBL20847604 | 0.84 | SLC6A2 (0.38) | SLC6A2SLC6A4PYCR1HDAC6HDAC8 | |
| SCHEMBL20847664 | 0.84 | ESR1 (0.38) | HDAC6HDAC8HDAC3HDAC11ALDH1A1 | |
| SCHEMBL20847602 | 0.82 | AGER (0.38) | SLC6A2SLC6A4HDAC6HDAC8HDAC3 | |
| SCHEMBL20847642 | 0.81 | SLC6A4 (0.35) | SLC6A2SLC6A4HDAC6HDAC8KDM4E | |
| SCHEMBL20847669 | 0.81 | AGER (0.40) | SLC6A2SLC6A4HDAC6PSEN1PSEN2 | |
| SCHEMBL20847622 | 0.80 | L3MBTL1 (0.40) | PYCR1ALDH1A1 | |
| SCHEMBL20847740 | 0.80 | NSD2 (0.47) | SLC6A2SLC6A4 | |
| SCHEMBL20847575 | 0.79 | AGER (0.42) | SLC6A2SLC6A4PSEN1PSEN2APH1B | |
| SCHEMBL20847775 | 0.79 | KMT2A (0.44) | HDAC6HDAC8HDAC3HDAC11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019056120-A1 | PENTAFLUOROPHENYL SULFONAMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | DALRIADA THERAPEUTICS INC. (CA) | 2019-03-28 | — | — | WO | disclosed |