Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20847629 | 0.81 | HTR2A (0.34) | — | |
| SCHEMBL20847643 | 0.76 | CXCR4 (0.37) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20847594 | 0.76 | STAT3 (0.38) | SMN1; SMN2TDP1KMT2A | |
| SCHEMBL20847650 | 0.75 | ALDH1A1 (0.35) | CYP2D6 | |
| SCHEMBL20847761 | 0.75 | SLC6A2 (0.40) | MAPTSMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20847720 | 0.72 | ALDH1A1 (0.41) | MAPTSMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20847666 | 0.70 | SLC6A3 (0.42) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20847664 | 0.70 | ESR1 (0.38) | — | |
| SCHEMBL20847604 | 0.70 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL22593297 | 0.69 | SMN1; SMN2 (0.52) | RAB9ATSHRMAPTSMN1; SMN2LIN28A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019056120-A1 | PENTAFLUOROPHENYL SULFONAMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | DALRIADA THERAPEUTICS INC. (CA) | 2019-03-28 | — | — | WO | disclosed |