Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | RORB | Q92753 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20847761 | 0.97 | SLC6A2 (0.40) | ALDH1A1SLC6A2SLC6A3KMT2AMEN1 | |
| SCHEMBL20847791 | 0.82 | SLC6A2 (0.42) | ALDH1A1SLC6A2SLC6A3SMN1; SMN2SLC6A4 | |
| SCHEMBL20847474 | 0.79 | SLC6A2 (0.42) | ALDH1A1SLC6A2SLC6A3SMN1; SMN2SLC6A4 | |
| SCHEMBL20847602 | 0.77 | AGER (0.38) | ALDH1A1SLC6A2SLC6A3KMT2AMEN1 | |
| SCHEMBL20847502 | 0.76 | RIPK1 (0.35) | — | |
| SCHEMBL20847669 | 0.76 | AGER (0.40) | ALDH1A1SLC6A2SLC6A3KMT2AMEN1 | |
| SCHEMBL20847575 | 0.75 | AGER (0.42) | ALDH1A1SLC6A2SLC6A3KMT2AMEN1 | |
| SCHEMBL20847704 | 0.72 | RAB9A (0.46) | SLC6A2SLC6A3KMT2ASMN1; SMN2SLC6A4 | |
| SCHEMBL20847500 | 0.71 | RIPK1 (0.31) | — | |
| SCHEMBL20847654 | 0.71 | ALDH1A1 (0.38) | ALDH1A1SLC6A2SLC6A3KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019056120-A1 | PENTAFLUOROPHENYL SULFONAMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | DALRIADA THERAPEUTICS INC. (CA) | 2019-03-28 | — | — | WO | disclosed |