Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20847602 | 0.78 | AGER (0.38) | SLC6A3SLC6A2SLC6A4HDAC8HDAC6 | |
| SCHEMBL20847474 | 0.77 | SLC6A2 (0.42) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL20847650 | 0.77 | ALDH1A1 (0.35) | HDAC8HDAC6 | |
| SCHEMBL20847669 | 0.77 | AGER (0.40) | SLC6A3SLC6A2SLC6A4HDAC6 | |
| SCHEMBL20847664 | 0.77 | ESR1 (0.38) | OPRM1HDAC8HDAC6 | |
| SCHEMBL20847604 | 0.77 | SLC6A2 (0.38) | SLC6A3SLC6A2SLC6A4HDAC8HDAC6 | |
| SCHEMBL20847477 | 0.75 | SLC6A2 (0.39) | SLC6A2SLC6A4TAAR1HDAC8HDAC6 | |
| SCHEMBL20847575 | 0.75 | AGER (0.42) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL20847492 | 0.75 | HDAC8 (0.37) | SLC6A3SLC6A2SLC6A4HDAC8HDAC6 | |
| SCHEMBL20847500 | 0.75 | RIPK1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019056120-A1 | PENTAFLUOROPHENYL SULFONAMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | DALRIADA THERAPEUTICS INC. (CA) | 2019-03-28 | — | — | WO | disclosed |