SCHEMBL20858019

SCHEMBL20858019

CC(C)(C)c1ccc2c(c1)c1cc(C(C)(C)C)cc3c4cc5c(-c6ccccc6)c6cc7c(cc6c(-c6ccccc6)c5cc4n2c13)c1cc(C(C)(C)C)cc2c3cc(C(C)(C)C)ccc3n7c21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SERPINE1 P05121 3/20 0.36
HTR1D P28221 1/20 0.36
PGR P06401 1/20 0.36
RORA P35398 1/20 0.36
RORC P51449 1/20 0.36
RORB Q92753 1/20 0.36
DNMT1 P26358 3/20 0.36
KIF11 P52732 3/20 0.36
ABCG2 Q9UNQ0 1/20 0.32
NPC1 O15118 1/20 0.31
ALDH1A1 P00352 1/20 0.31
PLA2G1B P04054 1/20 0.31
NFKB1 P19838 1/20 0.31
CASP3 P42574 1/20 0.31
RAB9A P51151 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31
SENP8 Q96LD8 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP6 Q9GZR1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21126565 0.97 SERPINE1 (0.40) SERPINE1HTR1DPGRRORARORC
SCHEMBL21126563 0.95 SERPINE1 (0.36) SERPINE1HTR1DPGRRORARORC
SCHEMBL20858021 0.91 HTR1D (0.38) SERPINE1HTR1DPGRRORARORC
SCHEMBL21126566 0.91 DNMT1 (0.37) SERPINE1HTR1DPGRRORARORC
SCHEMBL20857946 0.88 ABL1 (0.33) SERPINE1HTR1DPGRRORARORC
SCHEMBL25478629 0.88 SERPINE1 (0.37) SERPINE1HTR1DPGRRORARORC
SCHEMBL20857985 0.87 PGR (0.44) HTR1DPGRRORARORCRORB
SCHEMBL25478624 0.86 HTR1D (0.42) HTR1DPGRRORARORCRORB
SCHEMBL20857875 0.86 HTR1D (0.44) HTR1DPGRRORARORCRORB
SCHEMBL20857917 0.86 HTR1D (0.44) HTR1DPGRRORARORCRORB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230128708-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND NOVEL COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2023-04-27 US disclosed
US-20230128708-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND NOVEL COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2023-04-27 US disclosed
US-11569449-B2 Organic electroluminescence device and novel compound IDEMITSU KOSAN CO., LTD. (JP) 2023-01-31 US disclosed
US-20210336149-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2021-10-28 US disclosed
WO-2021065772-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC APPLIANCE 出光興産株式会社 2021-04-08 WO disclosed
EP-3723149-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND NOVEL COMPOUND Idemitsu Kosan Co., Ltd (JP) 2020-10-14 EP disclosed
US-10680181-B2 Organic electroluminescence device and novel compound IDEMITSU KOSAN CO., LTD. (JP) 2020-06-09 US disclosed
US-10672989-B2 Organic electroluminescence device and novel compound IDEMITSU KOSAN CO., LTD. (JP) 2020-06-02 US disclosed
US-20190355914-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND NOVEL COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2019-11-21 US disclosed
US-20190221747-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND NOVEL COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2019-07-18 US disclosed
US-10249832-B1 Organic electroluminescence device and novel compound IDEMITSU KOSAN CO., LTD. (JP) 2019-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230128708-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND NOVEL COMPOUND PIEZO1, TMEM109, OXA1L SERPINE1 2457/4885HTR1D 1918/4885PGR 2808/4885
US-10249832-B1 Organic electroluminescence device and novel compound OR10J3, KCNH3, OR51E2 SERPINE1 4744/4885HTR1D 1886/4885PGR 3049/4885
US-10680181-B2 Organic electroluminescence device and novel compound PIEZO1, TMEM109, OXA1L SERPINE1 2457/4885HTR1D 1918/4885PGR 2808/4885
US-10672989-B2 Organic electroluminescence device and novel compound LEF1, OR10J3, LUC7L2 SERPINE1 4339/4885HTR1D 3558/4885PGR 3049/4885
US-20190355914-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND NOVEL COMPOUND PIEZO1, TMEM109, OXA1L SERPINE1 2457/4885HTR1D 1918/4885PGR 2808/4885
US-20190221747-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND NOVEL COMPOUND KCNN4, OR10J3, KCNN2 SERPINE1 3965/4885HTR1D 521/4885PGR 698/4885
US-11569449-B2 Organic electroluminescence device and novel compound PIEZO1, TMEM109, OXA1L SERPINE1 2457/4885HTR1D 1918/4885PGR 2808/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.