SCHEMBL20857985

SCHEMBL20857985

CC(C)(C)c1ccc2c(c1)c1cc(C(C)(C)C)cc3c4cc5c6ccccc6c6cc7c8cc(C(C)(C)C)cc9c%10cc(C(C)(C)C)ccc%10n(c7cc6c5cc4n2c13)c98

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 5/20 0.44
RORA P35398 5/20 0.44
RORC P51449 5/20 0.44
RORB Q92753 5/20 0.44
KIF11 P52732 2/20 0.41
HTR1D P28221 1/20 0.38
NR1H3 Q13133 1/20 0.36
DNMT1 P26358 3/20 0.35
ALDH1A1 P00352 2/20 0.33
NPC1 O15118 1/20 0.33
PLA2G1B P04054 1/20 0.33
NFKB1 P19838 1/20 0.33
CASP3 P42574 1/20 0.33
RAB9A P51151 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
SENP8 Q96LD8 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26760307 0.92 KIF11 (0.41) PGRRORARORCRORBKIF11
SCHEMBL25478624 0.90 HTR1D (0.42) PGRRORARORCRORBKIF11
SCHEMBL20857917 0.90 HTR1D (0.44) PGRRORARORCRORBKIF11
SCHEMBL20857875 0.90 HTR1D (0.44) PGRRORARORCRORBKIF11
SCHEMBL24960723 0.89 RORA (0.39) PGRRORARORCRORBKIF11
SCHEMBL20858005 0.89 KIF11 (0.45) PGRRORARORCRORBKIF11
SCHEMBL20858019 0.87 SERPINE1 (0.36) PGRRORARORCRORBKIF11
SCHEMBL17773992 0.85 KIF11 (0.38) PGRRORARORCRORBKIF11
SCHEMBL26261691 0.85 DNMT1 (0.39) PGRRORARORCRORBKIF11
SCHEMBL21126565 0.84 SERPINE1 (0.40) PGRRORARORCRORBKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230128708-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND NOVEL COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2023-04-27 US disclosed
US-20210336149-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2021-10-28 US disclosed
EP-3723149-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND NOVEL COMPOUND Idemitsu Kosan Co., Ltd (JP) 2020-10-14 EP disclosed
US-10680181-B2 Organic electroluminescence device and novel compound IDEMITSU KOSAN CO., LTD. (JP) 2020-06-09 US disclosed
US-10672989-B2 Organic electroluminescence device and novel compound IDEMITSU KOSAN CO., LTD. (JP) 2020-06-02 US disclosed
US-10658594-B2 Organic electroluminescence device and novel compound IDEMITSU KOSAN CO., LTD. (JP) 2020-05-19 US disclosed
US-20190355914-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND NOVEL COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2019-11-21 US disclosed
US-20190194215-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND NOVEL COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2019-06-27 US disclosed
US-10249832-B1 Organic electroluminescence device and novel compound IDEMITSU KOSAN CO., LTD. (JP) 2019-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230128708-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND NOVEL COMPOUND PIEZO1, TMEM109, OXA1L PGR 2808/4885RORA 2765/4885RORC 3050/4885
US-10249832-B1 Organic electroluminescence device and novel compound OR10J3, KCNH3, OR51E2 PGR 3049/4885RORA 1485/4885RORC 1267/4885
US-10658594-B2 Organic electroluminescence device and novel compound OR10J3, OR51E2, TRPC6 PGR 1054/4885RORA 283/4885RORC 399/4885
US-10680181-B2 Organic electroluminescence device and novel compound PIEZO1, TMEM109, OXA1L PGR 2808/4885RORA 2765/4885RORC 3050/4885
US-20190194215-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND NOVEL COMPOUND OR10J3, OR51E2, TRPC6 PGR 1054/4885RORA 283/4885RORC 399/4885
US-10672989-B2 Organic electroluminescence device and novel compound LEF1, OR10J3, LUC7L2 PGR 3049/4885RORA 1623/4885RORC 1686/4885
US-20190355914-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND NOVEL COMPOUND PIEZO1, TMEM109, OXA1L PGR 2808/4885RORA 2765/4885RORC 3050/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.