Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22930093 | 0.82 | LMNA (0.36) | ALDH1A1MAPK1L3MBTL1CA2KMT2A | |
| SCHEMBL24245482 | 0.73 | TPSAB1 (0.43) | ALDH1A1CA1CA2 | |
| SCHEMBL31171268 | 0.72 | KMT2A (0.57) | ALDH1A1MAPK1L3MBTL1CA2KMT2A | |
| SCHEMBL42974 | 0.72 | ALDH1A1 (0.68) | ALDH1A1MAPK1L3MBTL1CA1CA2 | |
| SCHEMBL21384971 | 0.71 | ALDH1A1 (0.46) | ALDH1A1MAPK1L3MBTL1CA1CA2 | |
| Bromide SCHEMBL7209454 | 0.71 | ALDH1A1 (0.66) | ALDH1A1MAPK1L3MBTL1CA1CA2 | |
| Hydrochloric Acid SCHEMBL42973 | 0.71 | ALDH1A1 (0.66) | ALDH1A1MAPK1L3MBTL1CA1CA2 | |
| SCHEMBL29011017 | 0.70 | ENPP2 (0.50) | ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL10676527 | 0.69 | AGXT (0.50) | ALDH1A1MAPK1CA1CA2KMT2A | |
| SCHEMBL23049788 | 0.69 | CYP19A1 (0.47) | ALDH1A1MAPK1L3MBTL1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10308686-B2 | Gamma-AApeptides with potent and broad-spectrum antimicrobial activity | UNIVERSITY OF SOUTH FLORIDA (US) | 2019-06-04 | — | — | US | disclosed |
| US-20190100559-A1 | GAMMA-AAPEPTIDES WITH POTENT AND BROAD-SPECTRUM ANTIMICROBIAL ACTIVITY | UNIVERSITY OF SOUTH FLORIDA (US) | 2019-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10308686-B2 | Gamma-AApeptides with potent and broad-spectrum antimicrobial activity | ANPEP, DNPEP, ENPEP | ALDH1A1 2713/4885MAPK1 4334/4885L3MBTL1 1008/4885 |
| US-20190100559-A1 | GAMMA-AAPEPTIDES WITH POTENT AND BROAD-SPECTRUM ANTIMICROBIAL ACTIVITY | ANPEP, DNPEP, ENPEP | ALDH1A1 2713/4885MAPK1 4334/4885L3MBTL1 1008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.