Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 5/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.43 |
| ▸ | TPSD1 | Q9BZJ3 | 3/20 | 0.43 |
| ▸ | TPSG1 | Q9NRR2 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22930093 | 0.79 | LMNA (0.36) | LMNASMN1; SMN2TP53MAPTALDH1A1 | |
| SCHEMBL2820683 | 0.76 | LMNA (0.61) | TPSAB1PRSS1TPSD1TPSG1LMNA | |
| SCHEMBL5485588 | 0.76 | LMNA (0.61) | TPSAB1PRSS1TPSD1TPSG1LMNA | |
| SCHEMBL20864067 | 0.73 | ALDH1A1 (0.37) | ALDH1A1CA1CA2 | |
| Acetic Acid SCHEMBL8324881 | 0.73 | LMNA (0.56) | LMNASMN1; SMN2PLAUTP53MAPT | |
| SCHEMBL8156969 | 0.72 | ALDH1A1 (0.58) | TPSAB1PRSS1TPSD1TPSG1LMNA | |
| SCHEMBL16258192 | 0.72 | ALDH1A1 (0.58) | TPSAB1PRSS1TPSD1TPSG1LMNA | |
| SCHEMBL18822922 | 0.70 | CA2 (0.47) | LMNAMAPTALDH1A1HTTCA2 | |
| SCHEMBL11069589 | 0.70 | IDO1 (0.51) | TPSAB1PRSS1TPSD1TPSG1MAPT | |
| SCHEMBL21771638 | 0.65 | LMNA (0.62) | TPSAB1PRSS1TPSD1TPSG1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3950004-A1 | TARGETED COMPOSITIONS | Arbutus Biopharma Corporation (CA) | 2022-02-09 | — | — | EP | disclosed |