SCHEMBL1762048

SCHEMBL1762048

CC(=O)OCC(N)(CO)CO

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
ALDH1A1 P00352 5/20 0.40
HSD17B10 Q99714 1/20 0.40
KDM4E B2RXH2 2/20 0.34
POLB P06746 1/20 0.34
GALR3 O60755 2/20 0.33
CHRM5 P08912 2/20 0.33
CHRM1 P11229 2/20 0.33
CHRM3 P20309 2/20 0.33
GAA P10253 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
PGR P06401 1/20 0.33
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
HTR1A P08908 1/20 0.33
CHRNB2 P17787 1/20 0.33
TBXA2R P21731 1/20 0.33
CHRNB4 P30926 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12191370 0.95 LMNA (0.41) LMNAMEN1KMT2AALDH1A1HSD17B10
SCHEMBL11245129 0.94 LMNA (0.36) LMNAMEN1KMT2AALDH1A1HSD17B10
SCHEMBL28232410 0.89 ALDH1A1 (0.41) LMNAMEN1KMT2AALDH1A1HSD17B10
SCHEMBL4688117 0.87 ALDH1A1 (0.46) LMNAALDH1A1HSD17B10GALR3CHRM5
Hydrochloric Acid SCHEMBL4955070 0.85 ALDH1A1 (0.43) LMNAALDH1A1HSD17B10GALR3CHRM5
Edetic Acid SCHEMBL7899139 0.82 TDP1 (0.45) LMNAHSD17B10KDM4ECHRM2TSHR
SCHEMBL9779164 0.81 ALDH1A1 (0.42) MEN1KMT2AALDH1A1
SCHEMBL20865657 0.81 ALDH1A1 (0.46) LMNAMEN1KMT2AALDH1A1HSD17B10
SCHEMBL7928706 0.80
SCHEMBL9778987 0.79 ALDH1A1 (0.39) LMNAALDH1A1HSD17B10GALR3CHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200276108-A1 PHARMACEUTICAL CREAM COMPOSITIONS OF OXYMETAZOLINE AND METHODS OF USE EPI HEALTH, LLC 2020-09-03 US claimed
US-20200188517-A1 PHARMACEUTICAL CREAM COMPOSITIONS AND METHODS OF USE EPI HEALTH, LLC 2020-06-18 US claimed
US-20190029996-A1 composition containing artesunate ZHAO MING (US) 2019-01-31 US claimed
US-20160279155-A1 NOVEL FORMULATIONS AEROMICS, INC. (US) 2016-09-29 US claimed
EP-3065729-A2 NOVEL FORMULATIONS Aeromics, Inc. (US) 2016-09-14 EP claimed
WO-2015069956-A2 NOVEL FORMULATIONS AEROMICS, LLC (US) 2015-05-14 WO claimed
EP-2089429-B1 PROCESS FOR PREPARING UNAGGREGATED ANTIBODY FC DOMAINS JANSSEN BIOTECH INC (US) 2014-11-26 EP claimed
US-8853371-B2 Process for preparing unaggregated antibody Fc domains JANSSEN BIOTECH, INC. (US) 2014-10-07 US claimed
US-20130098775-A1 Glucose biosensor with improved shelf life NOVA BIOMEDICAL CORPORATION (US) 2013-04-25 US claimed
WO-2013059534-A1 GLUCOSE BIOSENSOR WITH IMPROVED SHELF LIFE NOVA BIOMEDICAL CORPORATION (US) 2013-04-25 WO claimed
US-7816527-B2 Quinazoline-containing kits for labeling aldehyde or ketone moieties Life Technologies Corporation (US) 2010-10-19 US claimed
US-20090171072-A1 Process for Preparing Unaggregated Antibody FC Domains CENTOCOR ORTHO BIOTECH INC. 2009-07-02 US claimed
EP-1097171-B1 METHOD FOR PURIFYING HEMOGLOBIN BIOPURE CORP (US) 2006-12-06 EP claimed
EP-0432221-B1 ONE-STEP IN SITU HYBRIDIZATION ASSAY APROGENEX INC (US) 1997-05-28 EP claimed
US-12496308-B2 Methods of administering a pharmaceutically acceptable salt of 2-{[3,5-bis(trifluoromethyl)phenyl]carbamoyl}-4-chlorophenyl dihydrogen phosphate AEROMICS, INC. (US) 2025-12-16 US disclosed
EP-4630545-A1 METHOD FOR SEPARATING BETA-XYLOSIDASE ENZYME FROM AN ENZYME MIXTURE IFP Energies nouvelles (FR) 2025-10-15 EP disclosed
US-20250206765-A1 CRYSTALS AEROMICS, INC. (US) 2025-06-26 US disclosed
EP-0380313-A2 Field inversion electroblotting EASTMAN KODAK COMPANY (US) 1990-08-01 EP disclosed
EP-0365321-A2 Electrophoresis apparatus EASTMAN KODAK COMPANY (US) 1990-04-25 EP disclosed
US-4205130-A AFFINITY VHROMATORGAPHY, ISOELECTRIC FOCUSING VIHKO PIRKKO 1980-05-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250206765-A1 CRYSTALS MTAP, PLCG2, PLCG1 LMNA 3026/4885MEN1 2233/4885KMT2A 3403/4885
US-12496308-B2 Methods of administering a pharmaceutically acceptable salt of 2-{[3,5-bis(trifluoromethyl)phenyl]carbamoyl}-4-chlorophenyl dihydrogen phosphate SLC34A2, SLC20A2, SLC34A3 LMNA 4513/4885MEN1 1917/4885KMT2A 3383/4885
US-20200276108-A1 PHARMACEUTICAL CREAM COMPOSITIONS OF OXYMETAZOLINE AND METHODS OF USE PDE3A, TREH, VEGFA LMNA 2818/4885MEN1 3703/4885KMT2A 1761/4885
US-20160279155-A1 NOVEL FORMULATIONS AQP1, AQP4, AQP3 LMNA 3787/4885MEN1 1877/4885KMT2A 4121/4885
US-20200188517-A1 PHARMACEUTICAL CREAM COMPOSITIONS AND METHODS OF USE CUTA, KRT18, IL17A LMNA 1439/4885MEN1 4119/4885KMT2A 3287/4885
US-20190029996-A1 composition containing artesunate MTAP, PDF, GLS2 LMNA 1482/4885MEN1 4110/4885KMT2A 3120/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.