Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | NOS1 | P29475 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | LTK | P29376 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.39 |
| ▸ | PRKX | P51817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3064844 | 0.80 | NOS1 (0.63) | NOS1HSD17B10TDP1PLK4CHEK1 | |
| SCHEMBL2048983 | 0.77 | MAPT (0.41) | ADRA2AADRA2BNOS1HSD17B10TDP1 | |
| SCHEMBL5153625 | 0.76 | ADRA2A (0.56) | ADRA2AADRA2BTDP1KDM4EMAPT | |
| SCHEMBL18897739 | 0.75 | ADRA2A (0.48) | ADRA2AADRA2BMEN1MAPTHPGD | |
| SCHEMBL28846891 | 0.73 | ADRA2A (0.47) | ADRA2AADRA2BHSD17B10TDP1KDM4E | |
| SCHEMBL22015514 | 0.71 | PIK3CD (0.59) | NOS1HSD17B10TDP1PLK4CHEK1 | |
| SCHEMBL8219716 | 0.70 | ADRA2A (0.43) | ADRA2AADRA2BHSD17B10TDP1ROCK1 | |
| SCHEMBL22013890 | 0.69 | LMNA (0.47) | ADRA2AADRA2BHSD17B10TDP1KDM4E | |
| SCHEMBL4752843 | 0.68 | NOS1 (0.53) | NOS1HSD17B10TDP1PLK4CHEK1 | |
| SCHEMBL10944347 | 0.67 | ADRA2A (0.51) | ADRA2AADRA2BKDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019067864-A1 | COMBINATION PHARMACEUTICAL AGENTS AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2019-04-04 | — | — | WO | disclosed |